Results 31 to 40 of about 1,470 (180)
Infrared absorption spectra of a series of 2, 6-diamino and 2-amino-6hydroxy-8-choroalkyl purines [PDF]
, 2003 8-haloalky purines were synthesized and infrared analysis (IR) carried out on them. The syntheses as well as the ill analyses are reported. The purines synthesized and studied include (i) 2,6-diamin-8-Chloromethyl purines, (ii) 2, 6-diamin-8-chlorethyl
I. M., Ejimadu
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Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay
Advanced Science, EarlyView.This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao +6 more
wiley +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Particle compositions with a pre-selected cell internalization mode [PDF]
, 2012 A method of formulating a particle composition having a pre-selected cell internalization mode involves selecting a target cell having surface receptors and obtaining particles that have i) surface moieties, that have an affinity for or are capable of ...
Decuzzi, Paolo, Ferrari, Mauro
core +1 more source
A case of endonasal balloon‐assisted dacryoplasty after failure of endonasal dacryocystorhinostomy [PDF]
, 2020 n/
Alessandro Vinciguerra +3 more
core +1 more source
Advanced Science, EarlyView.This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang +9 more
wiley +1 more source
Advanced Science, EarlyView.This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma +16 more
wiley +1 more source
Human cytochrome b5 reductase: structure, function, and potential applications [PDF]
, 2014 Cytochrome b5 reductase is a flavoprotein that is produced as two different isoforms that have different localizations. The amphipathic microsomal isoform, found in all cell types with the exception of erythrocytes, consists of one hydrophobic membrane-
Elahian, F. +3 more
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Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert +5 more
wiley +1 more source
Mitomycin alkaloids: synthetic studies [PDF]
, 2009 2009 Spring.Includes bibliographical references.Documented herein are efforts towards the first asymmetric total synthesis of the mitomycin family of natural products.
Gubler, Daniel Alan
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