Results 101 to 110 of about 386,071 (373)
Addressing a weakness of anticancer therapy with mitosis inhibitors: Mitotic slippage
Molecular & Cellular Oncology, 2017 Mitosis inhibitors, which include antimicrotubule drugs, are chemotherapy agents that induce the arrest and apoptosis of mitotic cells. Mitotic slippage, in which mitotically arrested cells exit mitosis, limits the effectiveness of mitosis inhibitors. We
Riju S. Balachandran, Edward T. Kipreos
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The duration of mitosis and daughter cell size are modulated by nutrients in budding yeast
bioRxiv, 2016 The size of nearly all cells is modulated by nutrients. Thus, cells growing in poor nutrients can be nearly half the size of cells in rich nutrients. In budding yeast, cell size is thought to be controlled almost entirely by a mechanism that delays cell ...
Ricardo M. Leitao, D. Kellogg
semanticscholar +1 more source
Advanced Science, EarlyView.Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li +19 more
wiley +1 more source
Indeks Mitosis Venereal Sarcoma pada Anjing Lokal di Denpasar
Indonesia Medicus Veterinus, 2014 Penelitian ini bertujuan untuk mengetahui rataan indeks mitosis serta perbedaan rataan indeks mitosis kasus venereal sarcoma pada anjing lokal jantan dan betina di Denpasar.
Fathurohman Nasrudin +2 more
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Role of Intermediate Filaments in Vesicular Traffic
Cells, 2016 Intermediate filaments are an important component of the cellular cytoskeleton. The first established role attributed to intermediate filaments was the mechanical support to cells.
Azzurra Margiotta, Cecilia Bucci
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Advanced Science, EarlyView.CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian +12 more
wiley +1 more source
E3 Ubiquitin Ligase TRIM Proteins, Cell Cycle and Mitosis
Cells, 2019 The cell cycle is a series of events by which cellular components are accurately segregated into daughter cells, principally controlled by the oscillating activities of cyclin-dependent kinases (CDKs) and their co-activators.
Santina Venuto, Giuseppe Merla
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Importin-beta and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function [PDF]
, 2017 Protein conjugation with small ubiquitin-related modifier (SUMO) is a post-translational modification that modulates protein interactions and localisation.
Damizia, Michela +7 more
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Advanced Science, EarlyView.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Ki-67 and CDK1 control the dynamic association of nuclear lipids with mitotic chromosomes
Journal of Lipid ResearchNuclear lipids play roles in regulatory processes, such as signaling, transcriptional regulation, and DNA repair. In this report, we demonstrate that nuclear lipids may contribute to Ki-67-regulated chromosome integrity during mitosis.
Hsiao-Tang Hu +4 more
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