Results 131 to 140 of about 379,827 (391)

Effects of X-ray irradiation on human spermatogenesis [PDF]

open access: yes, 1972
Direct cell kill and inhibition of mitosis have been suggested as mechanisms to explain the occurrence of absolute sterility following the irradiation of the testes.
Paulsen, C. A., Thorslund, T. W.
core   +1 more source

Meiosis: an overview of key differences from mitosis.

open access: yesCold Spring Harbor Perspectives in Biology, 2015
Meiosis is the specialized cell division that generates gametes. In contrast to mitosis, molecular mechanisms and regulation of meiosis are much less understood. Meiosis shares mechanisms and regulation with mitosis in many aspects, but also has critical
H. Ohkura
semanticscholar   +1 more source

Blood Biomarker‐Based Predictive Indicator for Liver Metastasis in Alpha‐Fetoprotein‐Producing Gastric Cancer and Multi‐Omics Tumor Microenvironment Insights

open access: yesAdvanced Science, EarlyView.
Alpha‐fetoprotein‐producing gastric cancer (AFPGC), a rare and aggressive subtype of gastric cancer, presents a high risk of liver metastasis. This study introduces the ANLiM score, a blood biomarker‐based predictive indicator for assessing liver metastasis and immunotherapy response.
Yongfeng Ding   +26 more
wiley   +1 more source

Mitosis: Introduction [PDF]

open access: yesCell Cycle, 2002
Even before biochemical and genetic approaches were employed, many researchers were captivated and astounded by mitosis. Cell biologists have been enthralled by its sheer beauty for more than a century (Fig. 1). Yanagida, who probably contributed more to the genetic dissection of mitotic processes than any other scientist, described it as a "cellular ...
openaire   +3 more sources

Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems

open access: yesAdvanced Science, EarlyView.
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar   +10 more
wiley   +1 more source

Genome accessibility is widely preserved and locally modulated during mitosis

open access: yesGenome Research, 2015
Mitosis entails global alterations to chromosome structure and nuclear architecture, concomitant with transient silencing of transcription. How cells transmit transcriptional states through mitosis remains incompletely understood.
C. Hsiung   +10 more
semanticscholar   +1 more source

Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length

open access: yesAdvanced Science, EarlyView.
Different from mitosis, the female meiosis undergoes asymmetric division that produces haploid oocytes and polar body, which is essential for retaining maternal components to support subsequent fertilization and embryo development. However, the underlying mechanisms are still largely unknown.
Yu Li   +6 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

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