Results 131 to 140 of about 329,783 (340)
Advanced Science, EarlyView.Magnetoelectric nanoparticles (MENPs) serve as externally controlled, MRI‐activated theranostic agents for targeted cancer therapy by inducing electric field‐based ablation in solid tumors. MENPs enable simultaneous precise tumor ablation and MRI signal modulation, allowing real‐time treatment monitoring and prediction of therapeutic outcomes with no ...
John Michael Bryant +28 more
wiley +1 more source
Characterization of mitosis-specific phosphorylation of tumor-associated microtubule-associated protein [PDF]
, 2009 Kyung U. Hong +3 more
openalex +1 more source
His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models
Advanced Science, EarlyView.His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li +13 more
wiley +1 more source
Advanced Science, EarlyView.A mechanically tunable ECM platform is created by integrating dECM–alginate matrices with in‐bath tumor printing. The mechanically tunable ECM environment drives tumors to acquire hypoxia, mechanotransduction signaling, metastatic traits, and drug‐resistant phenotypes that collectively promote malignant transformation.
Seok‐Hyeon Lee +8 more
wiley +1 more source
Advanced Science, EarlyView.Collagen type I (Col I) is integrated with self‐assembling peptide RADA16 and loaded with anti‐bacterial peptide SAAP148 to develop a self‐assembled nano‐microstructure hydrogel (Col I‐RADA16‐SAAP148, CRS) without chemical cross‐linkers. CRS exhibits excellent mechanical properties, sustained SAAP148 release to inhibit bacterial infection, macrophage ...
Qian Liu +8 more
wiley +1 more source
Polo-like kinase-1 Inhibitors and the Antiandrogen Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling [PDF]
, 2022 Jesse C. Patterson +18 more
openalex +1 more source
Evolution: functional evolution of nuclear structure. [PDF]
, 2011 The evolution of the nucleus, the defining feature of eukaryotic cells, was long shrouded in speculation and mystery. There is now strong evidence that nuclear pore complexes (NPCs) and nuclear membranes coevolved with the endomembrane system, and that ...
Dawson, Scott C, Wilson, Katherine L
core
Advanced Science, EarlyView.Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng +20 more
wiley +1 more source
Chromosome movement in lysed mitotic cells is inhibited by vanadate. [PDF]
, 1978 Mitotic PtK1 cells, lysed at anaphase into a carbowax 20 M Brij 58 solution, continue to move chromosomes toward the spindle poles and to move the spindle poles apart at 50% in vivo rates for 10 min.
CANDE, W. Zacheus, Wolniak, S
core +1 more source