Results 131 to 140 of about 380,556 (390)

Getting In and Out of Mitosis [PDF]

open access: yesRambam Maimonides Medical Journal, 2011
(Excerpt) Mitosis is the process of one cell dividing into two replicate cells. This process is a universal one, occurring throughout the phyla. Mitosis is a fundamental process. Without it, life ceases to exist.
openaire   +4 more sources

Domain-adversarial neural networks to address the appearance variability of histopathology images

open access: yes, 2017
Preparing and scanning histopathology slides consists of several steps, each with a multitude of parameters. The parameters can vary between pathology labs and within the same lab over time, resulting in significant variability of the tissue appearance ...
Eppenhof, Koen A. J.   +4 more
core   +1 more source

Regulation of Op18 during Spindle Assembly in Xenopus Egg Extracts [PDF]

open access: yes, 2001
Oncoprotein 18 (Op18) is a microtubule-destabilizing protein that is negatively regulated by phosphorylation. To evaluate the role of the three Op18 phosphorylation sites in Xenopus (Ser 16, 25, and 39), we added wild-type Op18, a nonphosphorylatable ...
Andersen   +67 more
core   +4 more sources

AI‐Enhanced Surface‐Enhanced Raman Scattering for Accurate and Sensitive Biomedical Sensing

open access: yesAdvanced Intelligent Discovery, EarlyView.
AI‐SERS advances spectral interpretation with greater precision and speed, enhancing molecular detection, biomedical analysis, and imaging. This review explores its essential contributions to biofluid analysis, disease identification, therapeutic agent evaluation, and high‐resolution biomedical imaging, aiding diagnostic decision‐making.
Seungki Lee, Rowoon Park, Ho Sang Jung
wiley   +1 more source

Developing cell biology

open access: yeseLife, 2013
Experiments in Xenopus embryo extracts reveal that changes in cellular biochemistry cause mitotic spindles to decrease in size over the course of early development.
Daniel Needleman
doaj   +1 more source

The coordination of nuclear envelope assembly and chromosome segregation in metazoans

open access: yesNucleus, 2020
The nuclear envelope (NE) is composed of two lipid bilayer membranes that enclose the eukaryotic genome. In interphase, the NE is perforated by thousands of nuclear pore complexes (NPCs), which allow transport in and out of the nucleus. During mitosis in
Shiwei Liu, David Pellman
doaj   +1 more source

Mitosis: Introduction [PDF]

open access: yesCell Cycle, 2002
Even before biochemical and genetic approaches were employed, many researchers were captivated and astounded by mitosis. Cell biologists have been enthralled by its sheer beauty for more than a century (Fig. 1). Yanagida, who probably contributed more to the genetic dissection of mitotic processes than any other scientist, described it as a "cellular ...
openaire   +3 more sources

Case Series of Nizon‐Isidor Syndrome by Heterozygous Variants in MED12L With Further Evidence of Mitotic Instability in One Case With Diploid–Triploid Mosaicism

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nizon‐Isidor syndrome is a rare disorder caused by heterozygous variants in MED12L, with only eight documented cases in the literature. Here, we present three additional cases of this syndrome. Proband 1 was a 7‐year‐old female who presented with developmental delay, right‐leg hemihypertrophy, laryngeal cleft, esotropia, abnormal skin ...
Russell Stewart   +336 more
wiley   +1 more source

Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation

open access: yeseLife, 2018
Several studies have shown that RNAi-mediated depletion of splicing factors (SFs) results in mitotic abnormalities. However, it is currently unclear whether these abnormalities reflect defective splicing of specific pre-mRNAs or a direct role of the SFs ...
Claudia Pellacani   +9 more
doaj   +1 more source

Epstein–Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA‐DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset

open access: yesAnnals of Neurology, EarlyView.
Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap   +37 more
wiley   +1 more source

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