Results 151 to 160 of about 166,111 (267)

A Multicellular Coordinated Network Driving Lymphovascular Space Invasion in Endometrioid Endometrial Carcinoma

open access: yesCell Proliferation, EarlyView.
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo   +7 more
wiley   +1 more source

Diagnostic Utility of PRAME Immunohistochemistry for Distinguishing Acral Melanoma From Acral Melanocytic Nevi

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Introduction Preferentially expressed antigen in melanoma (PRAME) immunohistochemistry helps distinguish non‐acral melanocytic lesions, but few studies have addressed its value in acral lesions. We aimed to identify an optimal PRAME cut‐off score to differentiate acral melanoma (AM) from acral melanocytic nevi (AMN).
Kritsada Phatcharamaneepakorn   +4 more
wiley   +1 more source

Mitotic reactivation and transcriptional bursting govern transcriptional noise in the early Drosophila embryo. [PDF]

open access: yesDevelopment
Maillard L   +8 more
europepmc   +1 more source

A Unified Deep Learning Framework for Instance Segmentation Across Diverse Cytological Stains

open access: yesCytopathology, EarlyView.
Transformer‐based unified cytology segmentation across Papanicolaou, Feulgen and AgNOR achieves stain‐invariant performance. Mask2Former maximises boundary precision (AP75) on the combined dataset, enabling one model to replace multiple stain‐specific deployments without accuracy loss while simplifying clinical integration.
Luís Otávio Santos   +6 more
wiley   +1 more source

Diagnostic Utility of the Milan System for Reporting Salivary Gland Cytopathology With Cytohistological Correlation

open access: yesCytopathology, EarlyView.
This retrospective study reviews 111 salivary gland fine‐needle aspiration cytology (FNAC) cases collected over an 11‐year period and reclassifies them according to the Milan System for Reporting Salivary Gland Cytopathology. Cytology‐histopathology correlation was performed for excision specimens, confirming the system's accuracy in distinguishing non‐
Shifa F. Khan   +4 more
wiley   +1 more source

SOX2 phosphorylation during mitosis limits genomic damage. [PDF]

open access: yesGenes Dev
Williams CAC   +10 more
europepmc   +1 more source

S1 guideline sweat gland carcinoma

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The current classification of sweat gland carcinomas is based on histomorphological characteristics and distinguishes between more than 20 entities. Most patients are older, but some subtypes also affect middle‐aged and younger patients. The majority of tumors arise de novo. Sweat gland carcinomas have nonspecific clinical features.
Mirjana Ziemer   +19 more
wiley   +1 more source

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