Results 181 to 190 of about 163,907 (337)

The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability

open access: yesCytoskeleton, EarlyView.
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou   +6 more
wiley   +1 more source

Interaction Between Actin and Microtubules During Plant Development

open access: yesCytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu   +3 more
wiley   +1 more source

β‐Glucuronidase‐Responsive Albumin‐Binding Prodrug of Colchicine‐Site Binders for Selective Cancer Therapy

open access: yesChemMedChem, EarlyView.
This study presents a β‐glucuronidase‐responsive albumin‐binding prodrug enabling the selective release within the tumor microenvironment of an Isocombretastatin A‐4 analog. In triple‐negative breast cancer (TNBC) mouse models, this prodrug demonstrated significant tumor growth inhibition, highlighting potential for enhanced therapeutic selectivity and
Alexandra Bordes   +6 more
wiley   +1 more source

Embracing equity and excellence while constructing science teacher identities in urban schools: Voices of new Teachers of Color

open access: yesJournal of Research in Science Teaching, Volume 60, Issue 1, Page 196-233, January 2023., 2023
Abstract We explored how new Teachers of Color grappled with equity and excellence as they were constructing science teacher identities while learning to teach in a teacher education program committed to equity, justice, and excellence, and eventually teaching in urban schools where inequities and injustices persist.
Maria Varelas   +3 more
wiley   +1 more source

Plasticity of mitotic cyclins in promoting the G2-M transition. [PDF]

open access: yesJ Cell Biol
Crncec A   +7 more
europepmc   +1 more source

Markers for internal neoplasia in the horse

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 132-143, January 2023., 2023
The measurement of tumour markers in horses should be performed only in risk groups or in patients with suspicious clinical/laboratory findings (paraneoplastic syndromes). The results should be interpreted with caution as many factors (e.g., young age, pregnancy and inflammation) affect their concentration or activity.
Karolina Drozdzewska, Heidrun Gehlen
wiley   +1 more source

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