Results 171 to 180 of about 166,111 (267)

TRIM32 controls timely cell cycle exit in muscular differentiation through downregulation of c‐Myc mRNA

The FEBS Journal, EarlyView.
Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong, Elisa Lazzari, Sabrina Pacor, Simeone Dal Monego, Erica Piovesan, Danilo Licastro, Germana Meroni   +6 more
wiley   +1 more source

CTCF maintains centromere function and mitotic fidelity. [PDF]

J Cell Sci
Walsh E, Laskarzewski T, Maresca TJ, Stephens AD.   +3 more
europepmc   +1 more source

Mitosis at a glance.

Journal of oral and maxillofacial pathology : JOMFP, 2014
openaire   +2 more sources

Updates and controversies in contemporary grading of clear cell renal cell carcinoma and papillary renal cell carcinoma

Histopathology, EarlyView.
New concepts, innovations and some issues have emerged since the adoption a decade ago of WHO/ISUP grading for CCRCC and PRCC. Continued use of the WHO/ISUP grading for CCRCC and PRCC has been upheld by newer studies, and practice guidance for some of the grading issues, where data are available, is provided.
Gladell P. Paner, Mahul. B. Amin, Jung Woo Kwon, Liang Cheng, Holger Moch   +4 more
wiley   +1 more source

H3K9me2 is a determinant for the mitosis-to-meiosis transition in female germ cells. [PDF]

Cell Death Dis
Hu Y, Zhou H, Shi L, Liu K, Meng X, Guo X, Shan L, Hu F, Liu Y, Zhang T, Zhou Y.   +10 more
europepmc   +1 more source

Spatial transcriptomics reveals clonal relationships between intraductal carcinoma and adjacent invasive prostate cancer

Histopathology, EarlyView.
Spatial transcriptomics of six prostate samples reveals a close clonal relationship between high‐grade Prostatic Intraepithelial Neoplasia (HGPIN), Intraductal carcinoma (IDC) and adjacent invasive glands. In three samples, adjacent invasive glands had more copy number variants than HGPIN and IDC. Adjacent invasive glands were also placed at the end of
Hridya Harikumar, Myrthe de Waard‐van Baardwijk, Marit de Haan, Gregory van Beek, Karishma Lila, Martin E van Royen, Thierry PP van den Bosch, Mathijs A Sanders, Eric Bindels, Andrew Stubbs, Geert JLH van Leenders   +10 more
wiley   +1 more source

Dual Inhibition of TRIP13 and Aurora A Induces Mitotic DNA Damage and Concurrent Pyroptotic-Apoptotic Cell Death in Rb-Deficient Cancer Cells. [PDF]

Clin Cancer Res
Yapindi L, Ghosh S, Shen L, Diao L, Wang J, Johnson FM.   +5 more
europepmc   +1 more source

UK recommendations for Ki‐67 immunohistochemical staining and interpretation in breast cancer

Histopathology, EarlyView.
Where possible, a validated digital imaging system should be utilized. If this is not available, then intermediate scores (5%–30%) should be thoroughly assessed using the Ki‐67 International Working Group guidance. Difficult cases should be double scored.
Abeer M Shaaban, Andrew Dodson, Emad Rakha, Ian Ellis, Daniel Rea, Cecily Quinn, Elena Provenzano, Sarah Pinder, on behalf of the UK National Coordinating Committee for Breast Pathology (NCCBP), Association of Breast Pathology (ABP) and the UK National External Quality Assessment Scheme for Immunohistochemistry and In Situ Hybridisation (UK NEQAS ICC & ISH)   +9 more
wiley   +1 more source

Uncovering mitotic ultrastructure in the native hair follicle using volume electron microscopy. [PDF]

J Cell Sci
Jadav N, Velamoor S, Hazelton N, Reader K, Harland D, Bostina M.   +5 more
europepmc   +1 more source

Whole‐slide analysis of mitotic activity in melanoma reveals higher‐proliferation hotspots and distinct spatial patterns

Histopathology, EarlyView.
Whole‐slide analysis of melanoma identified higher‐proliferation mitotic hotspots than routine pathology assessment and revealed distinct spatial patterns of mitotic organization, highlighting the potential of computational mitosis mapping to provide insights beyond conventional mitotic counting.
Shlomo Tsuriel, Batel Gabay, Victoria Hannes, Rami R Hagege, Dov Hershkovitz   +4 more
wiley   +1 more source