Results 281 to 290 of about 379,827 (391)

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

The multifaceted functions of SPC25 in cancer: from molecular pathways to targeted therapy. [PDF]

Front Med (Lausanne)
Jin Y, Chen M, Chen F, Gao Z, Li X, Hu L, Cai D, Zhao S, Song Z.   +8 more
europepmc   +1 more source

Spindle Membrane in Meiosis of Pollen Mother Cells of <i>Tradescantia</i> and in Mitosis of Endosperm Cells of <i>Zephyranthes</i>

, 1964
Bungo Wada, Fukuichi Kusunoki
openalex   +2 more sources

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Mitotic MTH1 inhibitor karonudib kills epithelial ovarian cancer independent of platinum sensitivity. [PDF]

Exp Hematol Oncol
Hurley RM, Wagner JM, Kanakkanthara A, Venkatachalam A, Deisinger AM, Correia C, Schneider PA, Peterson KL, Macon EP, Heinzen EP, Sanjiv K, Hou X, Becker MA, Maurer MJ, Larson MC, Swisher EM, Li H, Oberg AL, Weroha SJ, Berglund UW, Helleday T, Kaufmann SH, Hendrickson AEW.   +22 more
europepmc   +1 more source

Curcumin ameliorates hyperuricemia and gout‐induced damage via modulating the ROS‐dependent NEK7‐NLRP3 inflammasome activation

Smart Molecules, EarlyView.
Curcumin inhibits the ROS/NEK7‐NLRP3 inflammasome pathway by reducing reactive oxygen species (ROS) levels and disrupting the association of the NEK7‐NLRP3 complex. These combined effects of curcumin result in suppression of the GSDMD‐N pyroptotic pore formation and subsequent reduction of IL‐1β release.
Zhengtian Zhao, Xiaowei Tong, Jing Sun, Jiaqi Lu, Guangyu Zhang, Qing Wang, Li Yang   +6 more
wiley   +1 more source

An Auxin Inducible Degradation System to Study Mklp2 Functions in MDCK Epithelial Cells. [PDF]

Biol Cell
Rodriguez M, Simon V, Delaval B, Vitre B.   +3 more
europepmc   +1 more source

Engineering Pt Single‐Atom Doped SeS2/Ti3CNTx MXene with Molecularly Imprinted Polymer for Precision Pancreatic Cancer Diagnostics: DFT and Molecular Dynamics Perspectives

Small Methods, EarlyView.
A novel approach is developed to pancreatic cancer screening by targeting the cyclophili‐B (CypB)protein using a molecularly imprinted polymer with the electrode material containing Pt single‐atom‐doped/SeS2‐Ti3CNTx MXene. The quantification of CypB in pancreatic cancer tissues provide an insight into the association of CypB with pancreatic cancer ...
Sathish Panneer Selvam, Shanmugasundaram Kamalakannan, Agalya Mathivanan, Sungbo Cho   +3 more
wiley   +1 more source

Exploring trichoblastic carcinoma of scalp through immunohistochemistry and histopathology. [PDF]

BMJ Case Rep
Raju A, Shetty J, Shetty V, L P.
europepmc   +1 more source

Part II Mechanism of Mitosis

, 1965
Bungo Wada
openalex   +2 more sources