Engineering Chromosome Bridges Through CRISPR/Cas9 to Decipher the Impact of Intercentromeric Distance on Resolution Dynamics. [PDF]
Anglada T+3 more
europepmc +1 more source
Prenatal alcohol exposure perturbs the development of radial glial cells in the fetal olfactory bulb
Prenatal alcohol exposure affects the development of radial glial cells (RGCs) in the embryonic mouse olfactory bulb. Ethanol administered at embryonic day 11, a time point when RGCs generate the largest number of mitral cells, caused G2/M arrest in RGCs, delaying their progression to mitosis and subsequent neuronal differentiation.
Yuka Imamura Kawasawa+3 more
wiley +1 more source
Summary Disulfidptosis is a newly recognized cell death induced by disulphide stress under glucose deprivation. However, its clinical implications in multiple myeloma (MM) remain largely unexplored. We identified disulfidptosis‐related genes via co‐expression analysis and developed a risk signature through univariate Cox, least absolute shrinkage and ...
Li Wang+4 more
wiley +1 more source
Dynamic regulation of Sec24C by phosphorylation and O-GlcNAcylation during cell cycle progression. [PDF]
Georgiou GR+5 more
europepmc +1 more source
Nuclear destabilisation – a possible genesis of cancer?
ABSTRACT This review examines the increasingly prominent role of mechanics within cancer formation and progression. The extremely varied and contradictory genetic landscape of cancer is in stark contrast to the seemingly universal mechanical characteristics of cancer cells and their tumour microenvironment, and mechanics may be a principal unifying ...
Daniel D. Scott+4 more
wiley +1 more source
Discovery of unique mitotic mechanisms in <i>Paradiplonema papillatum</i>. [PDF]
Akiyoshi B, Faktorová D, Lukeš J.
europepmc +1 more source
Sexual conflict as a constraint on asexual reproduction: an empirical review
ABSTRACT Theory predicts that facultatively asexual animals, which can leverage the advantages of both sexual and asexual reproduction, should outcompete obligately sexual and obligately asexual animals. Yet, paradoxically, obligate sexual reproduction predominates in many animal lineages, while the most flexible form of facultative asexuality (i.e ...
Daniela Wilner+2 more
wiley +1 more source
The cAMP-PKA signaling initiates mitosis by phosphorylating Bora. [PDF]
Zhu M+7 more
europepmc +1 more source
Associations between pathological features and radioactive iodine-refractory recurrent papillary thyroid carcinoma: with mutation analysis using recurrent samples. [PDF]
Nguyen TN+14 more
europepmc +1 more source