Results 181 to 190 of about 67,036 (249)

Factors that determine cell fate in mitotically arrested cancer cells. [PDF]

open access: yesFront Cell Dev Biol
Ashraf N   +6 more
europepmc   +1 more source

Synthetic Raphanobrassica Genome Reveals Functional and Evolutionary Insights Into Clubroot Resistance Genes on Chromosome R5

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Clubroot, a severe soil‐borne disease caused by Plasmodiophora brassicae, poses a severe threat to global production of Brassicaceae oilseed crops and vegetables. To date, there has been a serious lack of clubroot‐resistant germplasms in Brassica napus (AACC), necessitating the urgent development of novel disease‐resistant germplasm.
Xueqing Zhou   +12 more
wiley   +1 more source

Methionine Synthase Positively Regulates Plant Defence to Both RNA and DNA Viruses and Is Useful for Developing Broad‐Spectrum Antiviral Resistance in Crops

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Plant viruses frequently cause severe economic losses in worldwide crop production. Developing broad‐spectrum resistance is the most efficient approach for controlling plant viral diseases. In this work, we found that the 17K protein of barley yellow dwarf viruses (BYDVs), which has multiple functions in viral pathogenesis including acting as ...
Zhaohui Wang   +16 more
wiley   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

open access: yesPhotochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal   +3 more
wiley   +1 more source

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye   +5 more
wiley   +1 more source

Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes

open access: yesPhotochemistry and Photobiology, EarlyView.
Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto   +8 more
wiley   +1 more source

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