Results 41 to 50 of about 48,528 (228)

Clinical Severity Score System in Dogs with Degenerative Mitral Valve Disease [PDF]

, 2015
BACKGROUND: Several risk factors already have been determined for dogs with degenerative mitral valve disease (DMVD). Risk factors often have been considered in isolation and have not always taken into account additional information provided by the ...
Atkins, Borgarelli, Borgarelli, Borgarelli, Boswood, Boswood, Chetboul, DeFrancesco, Doxey, Ferasin, Fujii, Gill, Haggstrom, Haggstrom, Haggstrom, Haggstrom, Haggstrom, Haggstrom, Hezzell, Kittleson, Ljungvall, Lord, López-Alvarez, Miller, Moonarmart, Ohad, Olsen, Pedersen, Pedersen, Reynolds, Schober, Tarnow   +31 more
core   +2 more sources

Noonan Syndrome Spectrum Disorders Predispose to Systemic Lupus Erythematosus: Case Report and Critical Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou, Gillian I. Rice, James O'Sullivan, Ben Parker, Ian N. Bruce, Emma Burkitt‐Wright, Tracy A. Briggs   +6 more
wiley   +1 more source

«Edge-to-edge» mitral valve repair for septal myectomy versus isolated myectomy: a pilot randomized trial

Евразийский Кардиологический Журнал, 2023
Background. Septal myectomy  is currently the «gold» standard of surgical treatment  of patients with obstructive  hypertrophic  cardiomyopathy.  In some  cases,  isolated septal myectomy does  not eliminate SAM-induced mitral insufficiency.
A. S. Zalesov, D. Y. Kozmin, S. A. Budagaev, A. V. Afanasyev, R. M. Sharifulin, S. I. Zheleznev, A. V. Bogachev-Prokophiev, A. M. Chernyavsky   +7 more
doaj   +1 more source

Marfan Syndrome Associated With Intellectual Disability and Behavioral Anomalies: Further Evidence for the Effect of Compound Heterozygous Variants in FBN1 on Phenotypic Severity

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Marfan syndrome (MFS) is a rare connective tissue disorder characterized by involvement of the cardiovascular, ocular, and musculoskeletal systems. Pathogenic variants in FBN1 cause most of the MFS cases; however, intellectual disability (ID) is rarely observed. A non‐consanguineous Pakistani family with four affected individuals was recruited.
Azmatullah Khan, Naseebullah Kakar, Ainullah Kakar, Malte Spielmann, Sajid Malik   +4 more
wiley   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Changes in left atrial deformation in hypertrophic cardiomyopathy: Evaluation by vector velocity imaging. [PDF]

, 2012
OBJECTIVES: Hypertrophic cardiomyopathy (HCM) represents a generalized myopathic process affecting both ventricular and atrial myocardium. We assessed the global and regional left atrial (LA) function and its relation to left ventricular (LV) mechanics ...
Badran, HM, Faheem, N, Hassan, H, Nazmy, A, Saadan, H, Soltan, G, Yacoub, MH   +6 more
core   +2 more sources

A Meta‐Analysis and Simplified Nomenclature for Diagonal Coronary Artery and Ramus Intermedius Across Adult and Pediatric Hearts

Clinical Anatomy, EarlyView.
ABSTRACT Anatomical descriptions of left‐sided oblique coronary branches remain inconsistent, hindering imaging interpretation and surgical planning. To quantify the prevalence, branching patterns and morphometry of the ramus intermedius (RI) and diagonal branches, and propose a unified nomenclature.
Yuqian Dai, Sabrina Constantini, Michael J. Montalbano, Marios Loukas   +3 more
wiley   +1 more source

Clinical assessment and echocardiography follow-up results of the children with acute rheumatic fever

American Journal of Experimental and Clinical Research, 2016
Acute rheumatic fever (ARF) is an inflammatory collagenous tissue disease which shows its cardinal signs in joints, heart, skin and nervous system while affecting whole connective tissue system more or less.
Ahmet Basturk, Kazim Oztarhan, Sultan Kavuncuoglu, Cemal Polat   +3 more
doaj   +2 more sources

Maternal Cardiovascular Impairment in Pregnancies Complicated by Severe Fetal Growth Restriction [PDF]

, 2012
—Fetal growth restriction and preeclampsia are both conditions of placental etiology and associated to increased risk for the long-term development of cardiovascular disease in the mother. At presentation, preeclampsia is associated with maternal global
Liberati, M, Melchiorre, K, Sutherland, GR, Thilaganathan, B   +3 more
core   +1 more source

Commissural Misalignment Following Valve‐in‐Valve Transcatheter Aortic Valve Implantation

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Data on commissural misalignment (CMA) during valve‐in‐valve transcatheter aortic valve implantation (ViV‐TAVI) for valve failure after surgical aortic valve replacement (SAVR) is scarce. Aims To study the impact of CMA on clinical and hemodynamic outcomes following ViV‐TAVI for failed SAVR.
Matthias Raschpichler, Johannes Rotta Detto Loria, Vivek Patel, Thilo Noack, Karoline Nüsser, Oliver Dumpies, Dhairya Patel, Takashi Nagasaka, Prateek Madaan, Aakriti Gupta, Holger Thiele, Michael A. Borger, Raj Makkar, Mohamed Abdel‐Wahab   +13 more
wiley   +1 more source