Results 141 to 150 of about 102,012 (266)

Comprehensive Assessment of the KDM2B‐Associated Neurodevelopmental Disorder and the 12q24.31 Microdeletion Syndrome

Clinical Genetics, EarlyView.
We set out to characterize genotype–phenotype correlations in the recently delineated KDM2B‐associated neurodevelopmental disorder. We observe a highly penetrant CxxC domain‐related phenotype with distinct facial features supported by GestaltMatcher. In contrast, our findings point to variable expressivity and incomplete penetrance of loss‐of‐function ...
Amber S. E. van Oirsouw, Tzung‐Chien Hsieh, Martijn Koetsier, Abdulrazak Alali, Fatimah Albuainain, Elena Bacchelli, Tahsin Stefan Barakat, Yline Capri, Sandra Chantot‐Bastaraud, Valeria Capra, Deanna Alexis Carere, Emma Clement, Nour Elkhateeb, Madeleine Franchi, Jing‐Mei Li, Nicole Matthews, Vanda McNiven, Sarju G. Mehta, Masayuki Nakamura, Chanika Phornphutkul, Nicole Revencu, Marcello Scala, Natalie Shallow, Jennifer Stefanich, Marta Viggiano, Paola Visconti, Susan Walker, Federico Zara, Mariëlle Alders, Bobby P. C. Koeleman, Renske Oegema   +30 more
wiley   +1 more source

Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation

Acta Medica Indonesiana
Functional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle.
Prima Almazini
doaj   +2 more sources

Primary cardiac T‐cell rich large B‐cell lymphoma causing aortic stenosis with metastasis in a Warmblood

Equine Veterinary Education, EarlyView.
Summary An 18‐year‐old Warmblood mare was presented to the Royal Veterinary College Equine Referral Hospital for investigation of progressive periocular and facial swelling, weight loss and tachycardia. Physical examination additionally identified bilateral pansystolic (grade 5/6 basilar left‐sided, 2/6 right‐sided), cardiac murmurs, submandibular ...
S. E. Talbot, F. Z. X. Lean, H. M. Martineau, B. Dunkel, J. Reed   +4 more
wiley   +1 more source

Interpretable machine learning models based on CMR radiomics for predicting left ventricular diastolic dysfunction in patients with metabolic‐associated steatotic liver disease and type 2 diabetes mellitus

Journal of Diabetes Investigation, EarlyView.
We developed an interpretable machine learning (ML) model combining cardiac magnetic resonance (CMR) radiomics and clinical data to assess left ventricular diastolic dysfunction (LVDD) risk in metabolic‐associated steatotic liver disease (MASLD)/type 2 diabetes mellitus (T2DM) patients, enabling proactive treatment.
Jinying Xia, Shaoyi Leng, Bin Xu, Guang Jin, Jianhui Li, Mingchen Zhang, Danzhen Yao, Ruiting Shen, Qifeng Hua   +8 more
wiley   +1 more source

Transcatheter Treatment Options for Functional Mitral Regurgitation: Which Device for Which Patients?

Interventional Cardiology: Reviews, Research, Resources
Mitral regurgitation is the most common valvular disease in the developed world, with approximately 24.2 million people being affected worldwide and a higher prevalence in older age groups.
Stephanie K Tom, Kanika Kalra, Emily Perdoncin, Andy Tully, Chandan M Devireddy, Errol Inci, Adam Greenbaum, Kendra J Grubb   +7 more
doaj   +1 more source

Pre‐anaesthetic risk assessment and management of dogs with myxomatous mitral valve disease: a spectrum of care narrative review

Journal of Small Animal Practice, EarlyView.
Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon, L. Köster, E. Vettorato, A. H. Estrada   +3 more
wiley   +1 more source

Population Pharmacokinetics of Sildenafil in Dogs With Naturally Occurring Pulmonary Hypertension

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics of sildenafil are ill‐defined in dogs with naturally occurring pulmonary hypertension (PH). Because the plasma concentrations of sildenafil have not been reported for dogs with this disease, this study aimed to describe the population pharmacokinetics of sildenafil in a sample of dogs with PH. Twenty client‐owned dogs with
Mariko Yata, Teresa C. DeFrancesco, John D. Bonagura, Mark G. Papich   +3 more
wiley   +1 more source

Pulmonary Vein Isolation in Elderly Patients With Atrial Fibrillation and Symptomatic Sick Sinus Syndrome: A Case Series

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT In patients with atrial fibrillation (AF), sinus node disease (SND) represents a potentially reversible concomitant condition. Initial treatment with catheter ablation (CA) aimed at restoration of sinus rhythm may provide an alternative to pacemaker implantation. In this case series, 15 elderly patients (>65 years) with AF and SND underwent CA,
Cerine Benachi, Patrick Nagel, Johannes Lucas, Ulf Landmesser, Gerhard Hindricks, Verena Tscholl, Sebastian Biewener, Martin Huemer, Philipp Attanasio, Tobias Schreiber   +9 more
wiley   +1 more source

Severe mitral regurgitation with bidirectional Coanda effect. [PDF]

Neth Heart J
Klop B, Timmermans NMAJ, van de Ven ART, Verberkmoes N, de Ridder S.   +4 more
europepmc   +2 more sources

Ischaemic mitral regurgitation [PDF]

Indian Journal of Thoracic and Cardiovascular Surgery, 2019
Om Prakash, Yadava, Song, Wan
openaire   +2 more sources