Results 151 to 160 of about 75,416 (289)

Compassionate use of the PASCAL transcatheter mitral valve repair system for patients with severe mitral regurgitation: a multicentre, prospective, observational, first-in-man study.

, 2017
BACKGROUND Severe mitral regurgitation is associated with impaired prognosis if left untreated. Using the devices currently available, transcatheter mitral valve repair (TMVr) remains challenging in complex anatomical situations.
Spargias, Konstantinos, Konstantinos Spargias, Florian Deuschl, Fam, Neil P, Webb, John, Edwards, Jeremy, Saibal Kar, Fabien Praz, Robert Schueler, John Webb, Kar, Saibal, Moody Makar, Michael Chrissoheris, Neil P Fam, Boone, Robert, Lutz Büllesfeld, Nickenig, Georg, Windecker, Stephan, Robert Moss, Praz, Fabien, Ted Feldman, Jeremy Edwards, Chrissoheris, Michael, Deuschl, Florian, Robert Boone, Büllesfeld, Lutz, Feldman, Ted, Aris Moschovitis, Schäfer, Ulrich, Stephan Windecker, Moschovitis, Aris, Makar, Moody, Moss, Robert, Georg Nickenig, Ulrich Schäfer, Schueler, Robert   +35 more
core   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12 ‐Related Developmental Disorders

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1619-1650, July 2026.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Echocardiographic Findings in Small‐Breed Dogs With Myxomatous Mitral Valve Disease and the Severity of Mitral Regurgitation, Heart Size and Clinical Signs Myxomatous Mitral Valve Disease in Dogs

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Myxomatous mitral valve disease (MMVD) is the most common acquired cardiac disorder in small‐breed dogs and is characterized by progressive mitral regurgitation that can lead to cardiac enlargement and clinical signs of heart failure. Accurate assessment of structural and hemodynamic changes using two‐dimensional, M‐mode and Doppler echocardiography is
Boshra Elyasi
wiley   +1 more source

Pre‐Sport Cardiac Evaluation in Children: Detection of Risks Other Than Sudden Cardiac Death

Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
In children who want to play sports, is a cardiac evaluation necessary only for sudden cardiac death? ABSTRACT Objective Sudden deaths may occur in children and adolescents due to unexpected cardiac problems during sports. This study aimed to screen for abnormalities that may lead to future morbidity in addition to the risk of sudden death and to ...
Mehmet Öncül, Abdulgani Gülyüz
wiley   +1 more source

The Diagnostic Odyssey of a Biochemically Confirmed Case of ML II: The First Western Patient With LYSET Deficiency

Clinical Genetics, Volume 110, Issue 1, Page 125-130, July 2026.
We identify a female patient with a homozygous nonsense variant (p.Gln38Ter) in the LYSET gene. This is the first western report of a challenging case of an extensive diagnostic odyssey and demonstrates that the LYSET gene must be considered in the differential diagnosis when M6P‐labeled lysosomal enzymes are altered.
Fernanda Sperb‐Ludwig, Taciane Alegra, Leonardo Martinello da Rosa, Nataniel Floriano Ludwig, Renata Voltolini Velho, Ida Vanessa Doederlein Schwartz   +5 more
wiley   +1 more source

3D‐Printed Dynamic Heart Model With Left‐Side Anatomy and Integrated Sensor for Edge‐to‐Edge Repair and Regurgitation Reduction

Advanced Materials Technologies, Volume 11, Issue 11, 5 June 2026.
This work presents a fully synthetic, 3D‐printed dynamic heart model with left‐side anatomy featuring sutured mitral valve chordae tendineae analogs, embedded actuators for physiologic wall contraction, and customized flexible pressure sensors for the left ventricle.
Alejandro Guillen Obando, Hongyi Shen, Myles McGovern, Yusen Zhang, Vivien Lin, Darryl Fu, Ryan Baumwart, Kaiyan Qiu   +7 more
wiley   +1 more source

Severe mitral regurgitation with bidirectional Coanda effect. [PDF]

Neth Heart J
Klop B, Timmermans NMAJ, van de Ven ART, Verberkmoes N, de Ridder S.   +4 more
europepmc   +2 more sources

Around and Through: Successful Mitral Paravalvular Leakage Closure Using Both Anterograde and Retrograde Approaches

Catheterization and Cardiovascular Interventions, Volume 107, Issue 7, Page 2179-2182, June 1, 2026.
ABSTRACT Paravalvular leak (PVL) is a recognized complication after surgical mitral valve replacement and may cause heart failure, pulmonary hypertension, or hemolysis when moderate or severe. Although redo surgery is the definitive treatment, it carries substantial risk in elderly patients or those with multiple prior cardiac surgeries.
Marco Garaventa, Luca Nai Fovino, Tommaso Fabris, Giuseppe Tarantini   +3 more
wiley   +1 more source

The Heart of the Thymus: A Rare Tale of Nonischemic Cardiomyopathy in the Absence of Myasthenia Gravis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Thymomas are rare epithelial tumors of the anterior mediastinum known for their association with autoimmune and paraneoplastic syndromes, most notably myasthenia gravis (MG). Cardiomyopathy is an exceptionally rare paraneoplastic manifestation.
Manish Barman, Bassem Al Hariri, Tasneem Babiker, Mohamed Gadkarem, Joudi Alhariri, Ahmad Alharafsheh   +5 more
wiley   +1 more source

New‐Onset Acute Heart Failure With Reduced Ejection Fraction Associated With Severe Microcytic Anemia

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Graphical abstract summarizing a case of new‐onset HFrEF associated with profound microcytic anemia, highlighting severe anemia as a potential reversible trigger of acute cardiac decompensation. ABSTRACT Severe microcytic anemia may serve as a potentially reversible precipitating factor in heart failure with reduced ejection fraction (HFrEF). This case
Annabel Ricci, Cassandra Hunt, Chabelly Gomez, Gerson Santafe, Aimee Gonzalez, Martha Duarte   +5 more
wiley   +1 more source