Results 151 to 160 of about 84,331 (274)

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, Volume 13, Issue 20, 9 April 2026.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

Advanced Science, Volume 13, Issue 22, 17 April 2026.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li, Muyin Liu, Chao Chen, Xinyan Li, Xiaopei Yan, Wentao Zhu, Wenyan Qiu, Qiyu Li, Xiangyu Sun, Chao Huang, Ming Yin, Zhangwei Chen, Yao Lu, Junbo Ge, Xiangqing Kong, Juying Qian, Yuqiong Chen   +16 more
wiley   +1 more source

Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair

Advanced Science, Volume 13, Issue 22, 17 April 2026.
This review examines the evolution of bioprinting toward minimally invasive in situ strategies for internal organ regeneration. It defines the technological roadmap from handheld systems to advanced minimally invasive bioprinting platforms, positioning soft robotics as a core enabler.
Duc Tu Vu, Nhu An Phan, Sy Trung Ngo, Minh Tri Phan, Thanh‐An Truong, Chi Cong Nguyen, Phuoc Thien Phan, Hoang‐Phuong Phan, Thanh Nho Do, Mai Thanh Thai   +9 more
wiley   +1 more source

A Meta‐Analysis and Simplified Nomenclature for Diagonal Coronary Artery and Ramus Intermedius Across Adult and Pediatric Hearts

Clinical Anatomy, Volume 39, Issue 3, Page 305-324, April 2026.
ABSTRACT Anatomical descriptions of left‐sided oblique coronary branches remain inconsistent, hindering imaging interpretation and surgical planning. To quantify the prevalence, branching patterns and morphometry of the ramus intermedius (RI) and diagonal branches, and propose a unified nomenclature.
Yuqian Dai, Sabrina Constantini, Michael J. Montalbano, Marios Loukas   +3 more
wiley   +1 more source

Reconsidering the Prognostic Role of the HALP Score in Rheumatic Mitral Stenosis

Clinical Cardiology, Volume 49, Issue 5, May 2026.
Muhammad Talha, Sawera Gul, Muhammad Faizan Khan   +2 more
wiley   +1 more source

Left Ventricular Outflow Tract Geometry as a Predictor of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation Using the Evolut Series

Catheterization and Cardiovascular Interventions, Volume 107, Issue 5, Page 1285-1292, April 1, 2026.
ABSTRACT Background Predicting the need for permanent pacemaker implantation (PPM) after transcatheter aortic valve implantation (TAVI) is crucial for procedural planning and patient counseling. Aims To evaluate whether left ventricular outflow tract (LVOT) morphology, specifically a tapered configuration, predicts conduction disturbances requiring PPM
Mahmoud Abdelshafy, Angela McInerney, Ahmed Elmeanawy, Paolo Alberto Del Sole, Max Wagener, Hatem Helal, Mahmoud Abozaid, Ashraf Alamir, Tamer Fouad, Alsayed Almarghany, Briain MacNeill, Osama Soliman, Darren Mylotte, Mohammad Abdelghani   +13 more
wiley   +1 more source

Unsupported valvuloplasty in children with congenital mitral valve anomalies. Late clinical results

Arquivos Brasileiros de Cardiologia, 2001
OBJECTIVE: To analyze late clinical evolution after surgical treatment of children, with reparative and reconstructive techniques without annular support. METHODS: We evaluated 21 patients operated upon between 1975 and 1998.
Lorier Gabriel, Kalil Renato A.K., Hoppen Gustavo R., Barcellos Christiano, Teleo Nicolas, Homsi Netto Abud, Gonzalez Javier, Prates Paulo R. L., Prates Paulo R., Sant'Anna João R. M., Nesralla Ivo A.   +10 more
doaj  

Geleophysic Dysplasia Associated With FBN1 Mutation: Clinical Course, Valvular Heart Disease, and Response to Recombinant Human Growth Hormone Therapy

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Geleophysic dysplasia (GD) is a rare genetic condition caused by pathogenic variants in either the ADAMTSL2 or FBN1 gene. We present a patient that combined clinical features consistent with GD, including short stature, delayed bone age, progressive congenital heart disease, and a happy, round face.
Ray Thomas Katbe, Laure Boutsen, Philippe A. Lysy   +2 more
wiley   +1 more source

Multisystem Sarcoidosis Presenting With Hypercalcemia, Lytic Bone Lesion, and Mesenteric Panniculitis in Chronic Kidney Disease

Clinical Case Reports, Volume 14, Issue 4, April 2026.
The clinical photograph shows bilateral leg swelling with right‐sided predominance and cutaneous changes. CT images (A–C) demonstrate abdominal and retroperitoneal lymphadenopathy, and image D shows a hypodense lytic spinal lesion, suggesting multifocal disease involving the abdomen, retroperitoneum, and spine.
Aishwarya Holi, Karuna Rayamajhi, Satya Rijal, Niket Shah, Aaron Sousa, Gina Chacon Osorio   +5 more
wiley   +1 more source

Outcome of bioprosthetic valve replacement in dogs with tricuspid valve dysplasia [PDF]

, 2017
Adin, Arai, Attenhofer Jost, Bloomfield, Brennan, Famula, Funayama, Griffiths, Liu, Massel, Monnet, Nakayama, Oliveira, Orton, Orton, Uechi   +15 more
core   +2 more sources