Results 31 to 40 of about 28,644 (225)

Refining a preclinical model of viral myocarditis in accordance with biotech standards

Animal Models and Experimental Medicine, EarlyView.
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen, Julia Riedesel, Juliane Stein, Brandon H. Greene, Svenja Rohde, Sonja Suess, Bjoern Keiner, Priya Panjwani, Padmapriya Ponnuswamy, Juan E. Camacho Londoño   +9 more
wiley   +1 more source

Echocardiographic navigation in transapical neochord mitral valve repair with significant mitral regurgitation

Вестник хирургии имени И.И. Грекова
INTRODUCTION. Significant mitral regurgitation is currently a widespread acquired valvular heart disease and is associated with a significant decrease in survival and deterioration in quality of life. One of the new, unclearly studied, minimally invasive
N. S. Titov, V. V. Komok, A. S. Nemkov, G. G. Khubulava   +3 more
doaj   +1 more source

SOX6 is expressed in various cell lineages in the developing mouse heart and contributes to proper valvuloseptal development

The Anatomical Record, EarlyView.
Abstract Cells derived from the endocardium, epicardium, cardiac neural crest, and second heart field play a critical role in the formation of the valvuloseptal structures of the heart. Previous studies have shown that the expression of the transcription factor SOX9 in these cell populations is essential in the regulation of this process.
Hannah G. Tarolli, Andrew B. Harvey, Inara Devji, Raymond N. Deepe, Jenna R. Drummond, Renélyn A. Wolters, Andy Wessels   +6 more
wiley   +1 more source

The Impact of a Visualized Steerable Sheath on Radiofrequency Catheter Ablation for First‐Time Atrial Fibrillation Ablation: A Prospective, Randomized, Single‐Blind Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background A 3D electroanatomical mapping (3D‐EAM) visualized steerable sheath was designed to improve catheter placement and reduce radiation exposure during ablation, an established treatment for atrial fibrillation (AF). However, prospective randomized data comparing the procedural and clinical outcomes of visualized and non‐visualized ...
Chun‐Kai Chen, Chih‐Chieh Yu, Min‐Tsun Liao, Hui‐Chun Huang, Yen‐Bin Liu   +4 more
wiley   +1 more source

Impact of MitraClip Program on the Volume and Outcomes of Mitral Valve Surgery: A Single-Center Retrospective Study

Cardiovascular Innovations and Applications, 2020
Surgical repair has been the standard therapy for severe mitral regurgitation causing symptoms or left ventricular dysfunction. Percutaneous mitral valve repair has become an appealing alternative approach for patients who are not suitable for surgery ...
Wei Zhang, Clifton Lewis, Sriniya Mallela, Ali Ebrahimi, Gregory Von Mering, Mustafa Ahmed   +5 more
doaj   +1 more source

A Randomized Controlled Trial Comparing the TruSteer and FXD Double Curve Delivery Systems for Left Atrial Appendage Occlusion With the Watchman FLX Pro Device—The GUIDE‐LAAO Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Deflectable delivery systems have been introduced to enhance coaxial alignment and procedural efficacy during left atrial appendage occlusion (LAAO), yet randomized comparisons with conventional fixed‐curve systems are lacking. Aims The GUIDE‐LAAO trial evaluated whether the TruSteer deflectable delivery system is non‐inferior to ...
Philippe Taieb, Marco Frazzetto, Pedro Soares Teixeira, Steven J. Filby   +3 more
wiley   +1 more source

Anomalous left coronary artery from the pulmonary artery: Outcomes and management of mitral valve

Frontiers in Cardiovascular Medicine, 2022
ObjectiveUse of concomitant mitral valve repair remains controversial in the anomalous left coronary artery from the pulmonary artery (ALCAPA) with mitral regurgitation (MR).
Juemin Yu, Juemin Yu, Qiushi Ren, Qiushi Ren, Xiaobing Liu, Tianyu Chen, Rong Liufu, Shusheng Wen, Jimei Chen, Jianzheng Cen, Jian Zhuang   +10 more
doaj   +1 more source

MELD score predicts outcomes in patients with advanced heart failure: A longitudinal evaluation

ESC Heart Failure, Volume 12, Issue 2, Page 839-847, April 2025.
Abstract Aims Advanced heart failure (AHF) is characterized by recurrent episodes of haemodynamic instability and frequent hospitalizations, leading to a progressive decline in quality of life and high mortality rates. The objectives of this study were to evaluate the effect of the model for end‐stage liver disease (MELD) score and its variations in ...
Francesco Curcio, Cristiano Amarelli, Rosaria Chiappetti, Irene Mattucci, Veronica Flocco, Mahmoud Issa Rammal, Ciro Abete, Francesca Mazzella, Ciro Maiello, Pasquale Abete, Francesco Cacciatore   +10 more
wiley   +1 more source

Longitudinal Outcomes Following Mitral Valve Repair for Infective Endocarditis

Microorganisms
Mitral valve repair is the ideal approach in managing mitral valve infective endocarditis for patients requiring surgery. However, viable repair is influenced by the extent of valve destruction and there can be technical challenges in reconstruction ...
Yuan Qiu, Lawrence Lau, Zaim Khan, David Messika-Zeitoun, Marc Ruel, Vincent Chan   +5 more
doaj   +1 more source

Percutaneous and minimally invasive approaches to mitral valve repair for severe mitral regurgitation-new devices and emerging outcomes

Annals of Cardiac Anaesthesia, 2015
Mitral valve disease is common in the United States and around the world, and if left untreated, increases cardiovascular morbidity and mortality. Mitral valve repair is technically more demanding than mitral valve replacement. Mitral valve repair should
Fadi E Shamoun, Ryan C Craner, Rita Von Seggern, Gerges Makar, Harish Ramakrishna   +4 more
doaj   +1 more source