Results 71 to 80 of about 35,850 (270)
ABSTRACT Background Paravalvular regurgitation (PVR) following transcatheter aortic valve replacement (TAVR) is a complication linked to poor outcomes. The prognostic impact of mild PVR, particularly in patients with elevated preprocedural left ventricular (LV) filling pressure, remains uncertain.
Shumpei Kosugi+12 more
wiley +1 more source
Mitral stenosis (MS) after mitral valve repair is a slowly progressive condition, usually detected many years after the index mitral valve surgery. It is defined as a transmitral pressure gradient (TMPG) of >5 mmHg or a mitral valve area (MVA)
Muhammad eShabsigh+6 more
doaj +1 more source
Abstract Aims Biomarkers are pivotal in the management of heart failure (HF); however, their lack of cardiac specificity could limit clinical utility. This study aimed to investigate the transcoronary changes and intracardiac production of these biomarkers.
Jie Ren+10 more
wiley +1 more source
Device‐based therapies for heart failure with preserved ejection fraction are limited, but the left atrial assist device pump is making progress as one option. Since the implantation site is unique, options for device orientation, driveline exteriorization, and exit sites must be demonstrated.
Chihiro Miyagi+5 more
wiley +1 more source
Mitral valve transcatheter edge‐to‐edge repair in the elderly—A safe and effective therapy
Mitral valve transcatheter edge‐to‐edge repair in elderly patients is safe and offers comparable mitral valve regurgitation reduction and symptom relief to younger patients. At 3 years, increased all‐cause mortality is observed in elderly patients with advanced heart failure and elevated EuroSCORE II.
Dominik Felbel+6 more
wiley +1 more source
Abstract Aims Wild‐type transthyretin cardiac amyloidosis (ATTRwt) is a cardiomyopathy causing myocardial hypoperfusion and impaired cardiac mitochondrial function. Trimetazidine is an antianginal agent used in patients with stable angina pectoris, which improves cardiac contractility and mitochondrial function.
Bertil Thyrsted Ladefoged+5 more
wiley +1 more source
Background The optimal treatment strategy following a failed mitral valve repair remains unclear. This study aims to compare and analyse available studies which report the clinical outcomes post mitral valve re-repair (MVr) or replacement (MVR) after a ...
Muthu Veerappan+3 more
doaj +1 more source
A novel mathematical technique to assess of the mitral valve dynamics based on echocardiography [PDF]
Purpose: The mechanics of the mitral valve leaflet as a nonlinear, inelastic and anisotropic soft tissue results from an integrated response of many mathematical/physical indexes' that illustrate the tissue. In the past decade, finite element modeling of complete heart valves has greatly aided evaluation of heart valve surgery, design of bioprosthetic ...
arxiv
Abstract Aims Ischaemic mitral regurgitation (MR) is a dynamic condition influenced by global and regional left ventricular remodelling as well as mitral valvular deformation. Exercise testing plays a substantial role in assessing the haemodynamic relevance of MR and is recommended by current guidelines.
Maximilian Spieker+14 more
wiley +1 more source
Abstract CNOT2 haploinsufficiency underlies a rare neurodevelopmental disorder named Intellectual Developmental disorder with NAsal speech, Dysmorphic Facies, and variable Skeletal anomalies (IDNADFS, OMIM 618608). The condition clinically overlaps with chromosome 12q15 deletion syndrome, suggesting a major contribution of CNOT2 haploinsufficiency to ...
Marcello Niceta+21 more
wiley +1 more source