Results 61 to 70 of about 1,743,769 (298)
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
Advanced Science, EarlyView.UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò +7 more
wiley +1 more source
JTCVS TechniquesObjectives: Some patients with degenerative mitral valve regurgitation have incidental coronary artery disease. When these patients are referred to our robotic cardiac surgery program, they are offered robotic mitral valve surgery combined with staged ...
Ali Hage, MD, MPH +4 more
doaj +1 more source
JA Clinical Reports, 2023 A 69-year-old male patient with mitral valve prolapse was scheduled for mitral valve plasty. Sixteen years earlier, he had undergone right open thoracotomy for esophageal cancer with subtotal esophagectomy, cervicothoraco-abdominal three-region ...
Yuri Sato +3 more
doaj +1 more source
Aortic and Mitral Valve Surgery on the Beating Heart
, 2003 This chapter contains sections titled: Introduction Rationale for avoiding cardioplegic arrest in aortic and mitral valve operations “Beating heart” surgery and “warm heart” surgery Aortic valve operations on the beating heart Mitral valve operations on ...
Sigler, Michael O +9 more
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Turner syndrome (TS) is associated with thoracic aortopathy and increased risk for aortic dissection, yet the natural history of aortic dilation is not well understood. We performed a retrospective longitudinal study of individuals with TS who participated in the TS Society of the United States Healthy Heart Project between 2003 and 2023 ...
Dylan Doerner +7 more
wiley +1 more source
Frontiers in Cardiovascular MedicineBackgroundThe clinical prognosis of mitral valve surgery at morning, afternoon, and evening is not yet clear. The aim of the study is to investigate the impact of different time periods of surgery in the morning, afternoon and evening on the short-term ...
Shuai Zheng +4 more
doaj +1 more source
Learning beyond the lab: A gamified approach to anatomy education in a museum‐based experience
Anatomical Sciences Education, EarlyView.Abstract Anatomy education, traditionally rooted in descriptive instruction and cadaveric dissection, is undergoing a significant transformation through the integration of educational technologies and contemporary pedagogical strategies. Among these, active learning methodologies, such as gamified‐based learning, have emerged as approaches designed to ...
Wendell Nunes da Silva +3 more
wiley +1 more source
SURGICAL TREATMENT INDICATIONS IN ACQUIRED MITRAL VALVULAR DISEASES
Eurasian Journal of Medicine, 2019 Surgery of mitral valve is performed as closed or open mitral commissurotomy, mitral valve repair surgery and mitral valve replacement. The purpose of mitral valve surgery is to relieve the symptoms unresponsive to medical therapy, to improve the quality
Necip Becit +2 more
doaj
Minimally Invasive Mitral Valve Surgery
, 2019 <p>This is my lecture about Minimally Invasive Mitral Valve Surgery for the Master in "Innovations in Cardiac Surgery" at Scuola Superiore Sant'Anna - Pisa, ITALY</p ...
Bianchi, G (6567173), Bianchi, G
core +1 more source