Results 131 to 140 of about 12,253 (284)
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Mixed-Criticality Scheduling in ROS2 for Autonomous Vehicles
Mixed-criticality scheduling is a key aspect in the design and development of real-time systems, especially in safety-critical applications like autonomous vehicles. The scheduling strategy aims to ensure that tasks with varying levels of criticality are
Bhaskar, Sudharsan Vaidhun +1 more
core
Mixed-criticality real-time task scheduling with graceful degradation
, 2018 ”The mixed-criticality real-time systems implement functionalities of different degrees of importance (or criticalities) upon a shared platform. In traditional mixed-criticality systems, under a hi mode switch, no guaranteed service is provided to lo ...
Arefin, Samsil
core
Decoupling Criticality and Importance in Mixed-Criticality Scheduling [PDF]
, 2018 Research on mixed-criticality scheduling has flourished since Vestal’s seminal 2007 paper, but more efforts are needed in order to make these results more suitable for industrial adoption and robust and versatile enough to influence the evolution of ...
Souto, P.F. +10 more
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Multiprocessor Scheduling of Mixed-Criticality Parallel Systems
, 2017 Motivated by the increasing trend in embedded systems towards platform integration, there has been an increasing research interest in scheduling mixed-criticality (MC) systems.
Liu, Guangdong
core
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Certification-Cognizant Mixed-Criticality Scheduling in Time-Triggered Systems [PDF]
, 2015 In embedded systems, there is a trend of integrating several different functionalities on a common platform. This has been enabled by increasing processing power and the arise of integrated system-on-chips.
Theis, Jens
core
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source