Results 121 to 130 of about 23,995,861 (305)

A longitudinal study of the predictors of quality of life in patients with major depressive disorder utilizing a linear mixed effect model

, 2014
We set out in this study to examine a longitudinal dataset using a linear mixed effects model. Our ultimate aim is to identify predictors of the quality of life (QOL) domains and items amongst patients suffering from major depressive disorders.
Pan, Ay-Woan;Chen, Yun-Ling;Chung, Ly-Inn;Wang, Jung-Der;Chen, Tsyr-Jang;Hsiung, Ping-Chuan, 潘璦琬 ;王榮德   +1 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Mixed-effects meta-regression model summary for accuracy studies, with stimulus type as the moderator.

Mixed-effects meta-regression model summary for accuracy studies, with stimulus type as the moderator.
Claude Alain (324898), Wenfu Bao (18475989), Monika Molnar (7440761), Michael Thaut (6375833)   +3 more
core   +1 more source

The analysis of longitudinal data using mixed model L-splines.

, 2006
L-splines are a large family of smoothing splines defined in terms of a linear differential operator. This article develops L-splines within the context of linear mixed models and uses the resulting mixed model L-spline to analyze longitudinal data from ...
Kenward, M. G., Brian R. Cullis, Welham, Sue J, Kenward, Michael G, Sue J. Welham, Robin Thompson, Cullis, Brian R, Thompson, Robin, Welham, S. J., Thompson, R., Michael G. Kenward, Cullis, B. R.   +11 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Mixed-effects meta-regression model summary for accuracy studies, with attention components as the moderator.

Mixed-effects meta-regression model summary for accuracy studies, with attention components as the moderator.
Claude Alain (324898), Wenfu Bao (18475989), Monika Molnar (7440761), Michael Thaut (6375833)   +3 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Individual tree inventory based on uncrewed aerial vehicle data: how to utilise stand-wise field measurements of diameter for calibration?

Silva Fennica
Uncrewed aerial vehicles (UAV) have great potential for use in forest inventories, but in practice they can be expensive for relatively small inventory areas as a large number of field measurements are needed for model construction. One proposed solution
Johanna Jääskeläinen, Lauri Korhonen, Mikko Kukkonen, Petteri Packalen, Matti Maltamo   +4 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Mixed model based inference in structured additive regression [PDF]

, 2006
Due to the increasing availability of spatial or spatio-temporal regression data, models that allow to incorporate the special structure of such data sets in an appropriate way are highly desired in practice.
Kneib, Thomas
core   +1 more source