Results 131 to 140 of about 23,995,861 (305)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Mixed-effects modeling for leader trustworthiness.

, 2019
Mixed-effects modeling for leader trustworthiness.
Ravi S. Kudesia (738850), Christopher S. Reina (6635687)   +1 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Model‐Based Meta‐Analysis With MonolixSuite: A Tutorial for Longitudinal Categorical and Continuous Data

CPT: Pharmacometrics & Systems Pharmacology
Model‐based meta‐analysis (MBMA) informs key drug development decisions by integrating data, published or unpublished, from multiple studies. Due to these various sources of information and the use of summary‐level data (e.g., mean responses over ...
Chloe Bracis, Amit Taneja, Yassine Kamal Lyauk, Heather Barcomb, Amparo de laPeña, Géraldine Cellière   +5 more
doaj   +1 more source

Future Scenarios of Global Urban Expansion and Carbon Emissions with National Heterogeneity: A Mixed-Effects Model Based on Urban Nighttime Lights

Remote Sensing
Cities play a pivotal role in environmental transformation and climate change mitigation. Urban expansion has substantial impacts on socioeconomic development and carbon emissions. This study develops a predictive model for future urban expansion and CO2
Jiaoyi Xu, Masanobu Kii, Yoshinori Okano, Chun-Chen Chou   +3 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

An Empirical Study on the Impact of Key Technology Configurations on Sales of Battery Electric Vehicles: Evidence from the Chinese Market

World Electric Vehicle Journal
In the global automotive industry’s transition towards electrification and intelligence, the influence of key technology configurations of battery electric vehicles (BEVs) on consumer purchasing decisions and market sales has become increasingly ...
Shufang Huang, Yunpeng Li, Zhen Xi
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Mixed exposures research agenda; a report by the NORA Mixed Exposures Team [PDF]

"Workers are continuously exposed to a wide variety of chemical substances, biological agents, physical agents, and other stressors encountered both in and out of the workplace.

core  

One-sided tolerance interval in a two-way balanced nested model with mixed effects [PDF]

, 2013
In many research areas (such as public health, environmental contamination, and others) one deals with the necessity of using data to infer whether some proportion (%) of a population of interest is (or one wants it to be) below and/or over some ...

core