Results 61 to 70 of about 5,282,104 (285)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The importance of the knowledge of flow stream in water sump pump [PDF]
, 2013 Numerous different experimental and numerical methods have been developed and are already improved in order to get rather good flow descriptions inside pump components. These calculations are generally realized assuming uniform and steady flow conditions,
SIMONET, Sophie +3 more
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Improving the Energy Efficiency of the Use of Oil Jet Pumps
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2022 The substantiation of the choice of design parameters characterizing the mutual orientation of the mixed flows and the ratio of the geometric dimensions of the elements of the flow path of the jet pump that provide an increase in the energy ...
D. A. Panevnyk
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The Impact of Pump Cavity Gaps on the Flow Characteristics of Helical Mixed-Flow Pumps
ActuatorsThe performance of pump-jet propulsion systems is critically important in defense and marine applications. However, their optimization has encountered bottlenecks due to a lack of theoretical understanding of underlying flow mechanisms.
Wei Han +3 more
doaj +1 more source
Applied Sciences, 2021 The spanwise distribution of impeller exit circulation (SDIEC) has an important influence on the performance of the impeller. To quantitatively study the influence of SDIEC on optimization results, a comprehensive optimization system composed of the ...
Mengcheng Wang +3 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The Mechanism of Air Blocking in the Impeller of Multiphase Pump
SeparationsThe exploitation and transportation of deep-sea and remote oil and gas fields have risen to become important components of national energy strategies. The gas–liquid separation and gas blocking caused by the large density difference between the gas and ...
Sicong Zhang +5 more
doaj +1 more source
Energies, 2017 The energy performance and radial force of a mixed flow pump with symmetrical and unsymmetrical tip clearance are investigated in this paper. As the tip clearance increases, the pump head and efficiency both decrease.
Yue Hao +5 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source