Results 111 to 120 of about 164,719 (284)

Sequence‐Encoded Frustration Directs the Formation of Abridged G‐Quadruplex Architectures

Angewandte Chemie, EarlyView.
Programmable frustration reshapes the free‐energy surface (FES) of guanine‐quadruplex (G4) folding, stabilizing an abridged G4 and a G‐triplex intermediate. ABSTRACT Frustration—competing interactions that cannot be simultaneously optimized—shapes energy landscapes in proteins and soft matter, but has rarely been exploited as a programmable design ...
Yuncheng Qian, Mohamed Y. Ali, Andreas I. Karsisiotis, Paul Dillon, Scarlett A. Dvorkin, Peter A. C. McPherson, Mateus Webba da Silva   +6 more
wiley   +2 more sources

Generally Applicable Q-Table Compression Method and Its Application for Constrained Stochastic Graph Traversal Optimization Problems

Information
We analyzed a special class of graph traversal problems, where the distances are stochastic, and the agent is restricted to take a limited range in one go.
Tamás Kegyes, Alex Kummer, Zoltán Süle, János Abonyi   +3 more
doaj   +1 more source

Bayesian Optimisation for the Experimental Sciences: A Practical Guide to Data‐Efficient Optimisation of Laboratory Workflows

Advanced Intelligent Systems, EarlyView.
This study provides an introduction to Bayesian optimisation targeted for experimentalists. It explains core concepts, surrogate modelling, and acquisition strategies, and addresses common real‐world challenges such as noise, constraints, mixed variables, scalability, and automation.
Chuan He, Martin Singull, T. Jesper Jacobsson   +2 more
wiley   +1 more source

A Diversity-Enhanced Constrained Particle Swarm Optimizer for Mixed Integer-Discrete-Continuous Engineering Design Problems

Advances in Mechanical Engineering, 2013
Engineering optimization problems usually contain various constraints and mixed integer-discrete-continuous types of design variables. We propose an efficient particle swarm optimization (PSO) algorithm for such problems.
Semin Chun, Young-Tark Kim, Tae-Hyoung Kim   +2 more
doaj   +1 more source

i‐Tac: Inverse Design of 3D‐Printed Tactile Elastomers with Tuneable Optical and Mechanical Properties

Advanced Intelligent Systems, EarlyView.
Inspired by the multi‐tissue architecture of the human fingertip dermis (A), this work introduces a mixture design using three PolyJet materials (AC/TM/GM) to expand the achievable elastomer property space (B). An inverse design pipeline (i‐Tac) is developed to map target optical/mechanical requirements to optimal material compositions (C), enabling ...
Wen Fan, Dandan Zhang
wiley   +1 more source

Adaptive Macroscopic Ensemble Allocation for Robot Teams Monitoring Spatiotemporal Processes

Advanced Intelligent Systems, EarlyView.
We propose an online, environment feedback‐driven macroscopic ensemble approach to adapt robot team task allocation in spatiotemporal environments by controlling robot populations rather than assigning individual robots, all while maintaining robust team performance even for small teams. Our simulation and experimental results show better or comparable
Victoria Edwards, Thales C. Silva, M. Ani Hsieh   +2 more
wiley   +1 more source

Optimizing 3D Bin Packing of Heterogeneous Objects Using Continuous Transformations in SE(3)

Advanced Intelligent Systems, EarlyView.
This article presents a method for solving the three‐dimensional bin packing problem for heterogeneous objects using continuous rigid‐body transformations in SE(3). A heuristic optimization framework combines signed‐distance functions, neural network approximations, point‐cloud bin modeling, and physics simulation to ensure feasibility and stability ...
Michele Angelini, Marco Carricato
wiley   +1 more source

An Intelligent Feature Engineering‐Driven Hybrid Framework for Adversarial Domain Name System Tunneling Detection

Advanced Intelligent Systems, EarlyView.
This study presents a novel framework that enhances the reliability of DNS traffic monitoring using a hybrid long short‐term memory‐deep neural network (LSMT‐DNN) architecture, enabling robust detection of adversarial DNS tunneling. The proposed framework leverages feature extraction from DNS traffic patterns, including domain request sequences, query ...
Ahmad Almadhor, Shtwai Alsubai, Monji Mohamed Zaidi, Natalia Kryvinska, Abdullah Al Hejaili, Sidra Abbas   +5 more
wiley   +1 more source

Beyond Chance-Constrained Convex Mixed-Integer Optimization: A Generalized Calafiore-Campi Algorithm and the notion of $S$-optimization

, 2015
The scenario approach developed by Calafiore and Campi to attack chance-constrained convex programs utilizes random sampling on the uncertainty parameter to substitute the original problem with a representative continuous convex optimization with $N ...
De Loera, J. A., La Haye, R. N., Oliveros, D., Roldán-Pensado, E.   +3 more
core  

Time‐Delayed Spiking Reservoir Computing Enables Efficient Time Series Prediction

Advanced Intelligent Systems, EarlyView.
This study proposes time‐delayed spiking reservoir computing (TDSRC) for efficient time series prediction. By concatenating time‐lagged states, TDSRC constructs an expanded readout feature vector without altering internal reservoir dynamics. This approach enables highly accurate forecasting with significantly fewer neurons, providing a resource ...
Pin Jin, Ren Cao, Zhongxue Gan, Siyang Leng   +3 more
wiley   +1 more source