Results 31 to 40 of about 781 (168)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

THE EFFECT OF TYPE ZEOLITE ON THE GAS TRANSPORT PROPERTIES OF POLYIMIDE-BASED MIXED MATRIX MEMBRANES

Reaktor, 2008
The permeation rates of O2, N2, CO2 and CH4 has been studied for polyimide-polyethersulfone (PI/PES) blends-zeolite mixed matrix membranes synthesized in our laboratory.
Tutuk Djoko Kusworo, Ahmad Fauzi Ismail, Azeman Mustafa, Kang Li   +3 more
doaj   +1 more source

PVA-Based Mixed Matrix Membranes Comprising ZSM-5 for Cations Separation

Membranes, 2020
The traditional ion-exchange membranes face the trade-off effect between the ion flux and perm-selectivity, which limits their application for selective ion separation.
Fangmeng Sheng, Noor Ul Afsar, Yanran Zhu, Liang Ge, Tongwen Xu   +4 more
doaj   +1 more source

Recent Progress in Mixed-Matrix Membranes for Hydrogen Separation

Membranes, 2021
Membrane separation is a compelling technology for hydrogen separation. Among the different types of membranes used to date, the mixed-matrix membranes (MMMs) are one of the most widely used approaches for enhancing separation performances and surpassing
Chong Yang Chuah, Xu Jiang, Kunli Goh, Rong Wang   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Synthesis and Characterisation of Self-Cleaning TiO₂/PES Mixed Matrix Membranes in the Removal of Humic Acid

Membranes, 2023
Membrane application is widespread in water filtration to remove natural organic matter (NOM), especially humic acid. However, there is a significant concern in membrane filtration, which is fouling, which will cause a reduction in the membrane life span,
Yan Kee Poon, Siti Kartini Enche Ab Rahim, Qi Hwa Ng, Peng Yong Hoo, Nur Yasmin Abdullah, Amira Nasib, Norazharuddin Shah Abdullah   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Natural gas purification by asymmetric membranes: An overview

Green Energy & Environment, 2021
Natural gas, as a very important source of energy and chemical feedstock, can be used in place of coal to lower net carbon dioxide emissions. Membrane separation technology is an attractive alternative for natural gas purification where the impurities ...
Xi Chen, Gongping Liu, Wanqin Jin
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source