Results 101 to 110 of about 5,170,261 (242)
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
, 2006 A traction-separation relation to model the fracture process is presented. The cohesive law captures the linear elastic and softening behaviour prior to fracture.
Högberg, J. Li,
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Modeling spatial trends and selecting tropical wheat genotypes in multi-environment trials
Crop Breeding and Applied BiotechnologyIn many cases, traditional analysis of breeding trials based on analysis of variance (ANOVA) do not allow a suitable genetic evaluation. Alternatively, mixed model-based approaches create the possibility of dealing with unbalanced data and modeling ...
Caique Machado e Silva +8 more
doaj
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Fracture and Structural Integrity, 2015 This paper is devoted to the analysis of the load path effect on I+II+III mixed mode fatigue crack propagation in a 316L stainless steel. Experiments were conducted in mode I+II and in mode I+II+III.
F. Fremy +3 more
doaj
FEBS Letters, EarlyView.Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Mixed-Mode Simulation and Analog Multilevel Simulation
, 1994 Mixed-Mode Simulation and Analog Multilevel Simulation addresses the problems of simulating entire mixed analog/digital systems in the time-domain. A complete hierarchy of modeling and simulation methods for analog and digital circuits is described ...
Newton, A. Richard +2 more
core +1 more source
Strong embedded discontinuities for simulating fracture in quasi-brittle materials [PDF]
, 2011 In this paper embedded strong discontinuities are used to model discrete cracking in materials like concrete. In the approach followed a discontinuous displacement field is considered and the deformation is localized at a surface of zero width.
core +3 more sources