Results 81 to 90 of about 651,282 (299)

State estimation for discrete-time Markovian jumping neural networks with mixed mode-dependent delays [PDF]

open access: yes, 2008
This is the post print version of the article. The official published version can be obtained from the link - Copyright 2008 Elsevier LtdIn this Letter, we investigate the state estimation problem for a new class of discrete-time neural networks with ...
Arik   +29 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A randomised trial and economic evaluation of the effect of response mode on response rate, response bias, and item non-response in a survey of doctors

open access: yesBMC Medical Research Methodology, 2011
Background Surveys of doctors are an important data collection method in health services research. Ways to improve response rates, minimise survey response bias and item non-response, within a given budget, have not previously been addressed in the same ...
Witt Julia   +6 more
doaj   +1 more source

Mixed Modes of Innovation [PDF]

open access: yesOECD Science, Technology and Industry Working Papers, 2012
This study uses exploratory data analysis techniques to develop typologies of innovation modes or strategies for groups of firms. Analysing micro-level survey data from 18 countries we identify five innovation modes. The coherence and relevance of the innovation modes is tested by using them as explanatory factors in equations explaining economic ...
openaire   +1 more source

Mixed signal approach for rapid prototyping of a compact smart pebble for sediment transport monitoring in river beds [PDF]

open access: yes, 2005
Low-cost accelerometers and gyro ICs were used to develop a smart sediment particle to study the sediment transport in rivers. With strap-down MEMS, battery, a processing subsystem and memory, this self contained unit captures semiprocessed data for ...
Kularatna, Nihal   +2 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Mixed mode oscillations and phase locking in coupled FitzHugh-Nagumo model neurons

open access: yes, 2018
We study the dynamics of a low-dimensional system of coupled model neurons as a step towards understanding the vastly complex network of neurons in the brain.
Aminzare, Zahra   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Evaluation of Mixed-mode Integral Invariant for Polymer Material Trough The Couple Experimental-Numerical Process

open access: yesEPJ Web of Conferences, 2010
Usually the element of real structures is subject of the mixed mode loadings. This fact can be explained by the elements geometry and the loading orientations.
Absi J., Dubois F., Pop O., Meite M.
doaj   +1 more source

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