Results 71 to 80 of about 5,170,261 (242)

Mixed Mode Crack Propagation in Iliac Bone

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2021
Bone is a complex material that can be regarded as an anisotropic elastic composite material. The problem of crack propagation in human bone is analyzed by using a generalization of the maximum tensile stress criterion (MTS).
Baesu E., Iliescu DM., Radoiu BV., Halichidis S.   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Measuring and testing the interview mode effect in mixed mode surveys

Statistica, 2014
Many studies are showing an increased tendency to use more than one data collection mode for a particular survey. However, mixed data collection modes may influence responses given by interviewees and require researchers to verify if differences in ...
Furio Camillo, Ida D'Attoma
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Fracture mechanisms and failure criteria of adhesive joints and toughened epoxy adhesives [PDF]

, 2010
PhDAdhesive bonded applications are used widely in industry because of significant advantages such as uniform stress distribution, and the ability to join different materials.
Xu, Botao
core   +4 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

On the Relative Advantage of Mixed-Mode versus Single-Mode Surveys

Survey Research Methods, 2013
Survey researchers increasingly use mixed-mode surveys for general population data collection because mixed-mode surveys are argued to provide lower selection error at constant budgets or lower variable costs at constant selection error.
Jorre Vannieuwenhuyze
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

One-Pot Preparation of Mixed-Mode Reversed-Phase Anion-Exchange Silica Sorbent and its Application in the Detection of Cyclopiazonic Acid in Feeds and Agricultural Products

Foods
A novel co-bonded octyl and pyridine silica (OPS) sorbent was prepared and applied for the solid phase extraction (SPE) of cyclopiazonic acid (CPA, a type of mycotoxin) in feed and agricultural products for the first time.
Xuan Hu, Li Liu, Maomin Peng, Dan Zheng, Hong Xia, Youxiang Zhou, Lijun Peng, Xitian Peng   +7 more
doaj   +1 more source