Results 71 to 80 of about 651,282 (299)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Single VDCC-Based Mixed-Mode First-Order Universal Filter and Applications in Bio-Signal Processing Systems

open access: yesTechnologies
This paper presents a compact mixed-mode first-order universal filter based on a single voltage differencing current conveyor (VDCC), which can function in all four possible operation modes, i.e., voltage mode (VM), trans-admittance mode (TAM), current ...
Pitchayanin Moonmuang   +3 more
doaj   +1 more source

[Multilingualism and Mixed-Mode Communication

open access: yes, 2023
Like other disciplines, the field of sociolinguistics is not a homogenous one. It rather comes in three “loosely connected waves” (Eckert 2012) with each wave applying specific sets of methods. How can we use methodological triangulation and combine these methods, both quantitative and qualitative in nature, to integrate the three waves of ...
openaire   +2 more sources

Characterizing mixed mode oscillations shaped by noise and bifurcation structure

open access: yes, 2010
Many neuronal systems and models display a certain class of mixed mode oscillations (MMOs) consisting of periods of small amplitude oscillations interspersed with spikes.
Juan Luis Cabrera   +6 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On the Relative Advantage of Mixed-Mode versus Single-Mode Surveys

open access: yesSurvey Research Methods, 2013
Survey researchers increasingly use mixed-mode surveys for general population data collection because mixed-mode surveys are argued to provide lower selection error at constant budgets or lower variable costs at constant selection error.
Jorre Vannieuwenhuyze
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mixed Mode Oscillation in FitzHugh-Rinzel Model

open access: yesپژوهش‌های ریاضی, 2021
FitzHugh-Nagumo-Rinzel model is an important model for the dynamics of single neuron. We observed some patterns of Bursting specially Mixed Mode Oscillation (MMO) in this model.
Mohammad Reza Razvan   +1 more
doaj  

Mixed mode oscillations in the Bonhoeffer-van der Pol oscillator with weak periodic perturbation [PDF]

open access: yes, 2013
Following the paper of K. Shimizu et al. (2011) we consider the Bonhoeffer-van der Pol oscillator with non-autonomous periodic perturbation. We show that the presence of mixed mode oscillations reported in that paper can be explained using the ...
Kutafina, E.
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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