Results 51 to 60 of about 5,170,261 (242)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Mixed-mode implementation of particle filters [PDF]

open access: yes
In this paper, we develop new mixed-mode implementations for particle filters and compare them to a digital implementation. The motivation for the mixed-mode implementation is to achieve low-power implementation of particle filters.
Subramanian, Shyam   +4 more
core   +2 more sources

Investigation of mixed mode-I/II fracture problems - Part 2: evaluation and development of mixed mode-I/II fracture criteria [PDF]

open access: yesFracture and Structural Integrity, 2016
In this study, experimental and numerical results of compact tension shear (CTS) specimen and a new specimen type under in-plane mixed mode (Mode-I/II) loading conditions are compared with existing inplane mixed mode fracture criteria to investigate ...
O. Demir, A. O. Ayhan
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Separation of sulphonamides on a C12-diol mixed-mode HPLC column and investigation of their retention mechanism

open access: yesOpen Chemistry
Sulphonamides exhibit broad-spectrum antibacterial effects. However, their extensive use poses health risks, such as antimicrobial resistance. Therefore, advanced and accurate analytical techniques are needed to monitor the presence of sulphonamide ...
Aral Hayriye, Altun Yekun
doaj   +1 more source

Investigation of Mixed-Mode I/II Fracture under Impact Loading Using Split-Hopkinson Pressure Bar

open access: yesApplied Sciences, 2020
Mixed-mode fracture of construction building materials under impact loading is quite common in civil engineering. The investigation of mixed-mode crack propagation behavior is an essential work for fundamental research and engineering application.
Fei Wang   +6 more
doaj   +1 more source

Residual strength evaluation under mixed mode loading [PDF]

open access: yesMATEC Web of Conferences, 2019
This work explores the failure resistance of fatigue damages with random orientation through a new computational framework. Such analytical model aims to enable designers to properly and quickly assess stress state and residual life under cyclic loading ...
Boljanović Slobodanka   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Missing mixed mode: elemental structures

open access: yesRevista Obets, 2012
One of the main concerns is the nature of the missing values. Let’s consider extremes for simplicity. If missing at random we have not to care about.
Antonio Alaminos Chica
doaj   +1 more source

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