Results 51 to 60 of about 4,719,547 (292)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Lifetime evaluation of concrete structures under sustained post-peak loading [PDF]

open access: yes, 2005
Experimental tests on crack propagation in concrete under constant post-peak loading are simulated using the finite element method and the cohesive crack model, in both Mode I and Mixed-mode conditions.
Silvio Valente   +3 more
core   +1 more source

Investigation of Mixed-Mode I/II Fracture under Impact Loading Using Split-Hopkinson Pressure Bar

open access: yesApplied Sciences, 2020
Mixed-mode fracture of construction building materials under impact loading is quite common in civil engineering. The investigation of mixed-mode crack propagation behavior is an essential work for fundamental research and engineering application.
Fei Wang   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

State estimation for discrete-time neural networks with Markov-mode-dependent lower and upper bounds on the distributed delays [PDF]

open access: yes, 2012
Copyright @ 2012 Springer VerlagThis paper is concerned with the state estimation problem for a new class of discrete-time neural networks with Markovian jumping parameters and mixed time-delays.
Liu, Y, Liu, X, Wang, Z
core   +1 more source

Separation of sulphonamides on a C12-diol mixed-mode HPLC column and investigation of their retention mechanism

open access: yesOpen Chemistry
Sulphonamides exhibit broad-spectrum antibacterial effects. However, their extensive use poses health risks, such as antimicrobial resistance. Therefore, advanced and accurate analytical techniques are needed to monitor the presence of sulphonamide ...
Aral Hayriye, Altun Yekun
doaj   +1 more source

Repeated weighting in mixed-mode censuses

open access: yesEconomics and Business Review, 2021
The main aim of the paper is to use the repeated weighting (RW) method on data from the National Census of Population and Housing 2011 (NCPH) and Labour Force Survey (LFS) to ensure consistency between margins of final tables derived from different ...
Szymkowiak Marcin, Wilak Kamil
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Missing mixed mode: elemental structures

open access: yesRevista Obets, 2012
One of the main concerns is the nature of the missing values. Let’s consider extremes for simplicity. If missing at random we have not to care about.
Antonio Alaminos Chica
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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