Results 111 to 120 of about 4,947,794 (321)

Remote Activation of Wnt Signaling and Cell Proliferation by E‐Cadherin Magnetomechanical Stimulation

Advanced Functional Materials, EarlyView.
A pioneering magnetogenetic toolkit enables non‐invasive, precise spatiotemporal modulation of intracellular Wnt/β‐catenin signaling. Functionalized magnetic nanoparticles (MNPs@E/EC15) target cellular E‐cadherins to generate localized magnetomechanical forces under low‐intensity magnetic fields.
Christian Castro‐Hinojosa, Pablo Martínez‐Vicente, Lucía G. Recaredo, Susel Del Sol‐Fernández, Pilar Gomollón‐Zueco, Yilian Fernández‐Afonso, Raluca M. Fratila, María Moros   +7 more
wiley   +1 more source

Optimization of methods for isolation and purification of outer membrane vesicles (OMVs) from Neisseria lactamica

Applied Microbiology and Biotechnology
Outer membrane vesicles (OMVs) are nanoparticles released by Gram-negative bacteria during growth, mainly under stress conditions. OMV-based vaccines have played an important role in vaccination against Neisseria meningitidis serogroup B (MenB ...
Ronaldo Moraes Preto, Vithória Carolyna Trindade dos Santos, Marcos Vinicius Santos Lordelo, Getúlio Henrique Ferreira Pereira, Luciana Cezar de Cerqueira Leite, Viviane Maimoni Gonçalves, Giovana Cappio Barazzone   +6 more
doaj   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

A mixed-mode LC-MS-based method for comprehensive analysis of NAD and related metabolites from biological sample matrices

Scientific Reports
Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite contributing to cellular energy needs and its decline is associated with age-related disorders.
Omprakash Nacham, Jordan W. Brown, Mohammad Mehdi Maneshi, Victoria Kurschner, Mike Sheehan, Renee Sadowski, Chris Ling, Nari Talaty, Robert Johnson, Andrew M. Swensen   +9 more
doaj   +1 more source

Sample Preparation Techniques for Growth-Promoting Agents in Various Mammalian Specimen Preceding MS-Analytics

Molecules
The misuse of growth-promoting drugs such as beta-2 agonists and steroids is a known problem in farming and sports competitions. Prior to the analysis of biological samples via liquid chromatography (LC)–mass spectrometry (MS) or gas chromatography (GC ...
Laura Klöppner, Lukas Corbinian Harps, Maria Kristina Parr   +2 more
doaj   +1 more source

Determination of Persistent and Mobile Organic Contaminants (PMOCs) in Water by Mixed-Mode Liquid Chromatography–Tandem Mass Spectrometry

, 2019
The presence of persistent and mobile organic contaminants (PMOC) in aquatic environments has become a matter of concern due to their ability of breaking through natural and anthropogenic barriers, even reaching drinking water.
José Benito Quintana (1732744), Rosa Montes (170013), Rosario Rodil (1732735), Rafael Cela (1732738)   +3 more
core   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

Advanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Advancing Wastewater Surveillance: Development of High-Throughput Green Robotic SPE-UPLC-MS/MS Workflow for Monitoring of 27 Steroids and Hormones

Applied Sciences
Conventional methods for testing steroids and hormones (SHs) in environmental samples are exhaustive, complex, and score poorly in sustainability matrices. Therefore, this study evaluates the automated sample preparation approach using the modular Biomek
Bhaskar Karubothula, Chaitanya Devireddy, Dnyaneshwar Shinde, Rizwan Shukoor, Ghenwa Hafez, Raghu Tadala, Samara Bin Salem, Wael Elamin, Grzegorz Brudecki   +8 more
doaj   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Application of Thiol-Modified Silica Hybrid Monoliths for Hydrophilic Interaction Capillary Liquid Chromatography

Sains Natural
A silica hybrid monolithic column modified with Thiol-group were successfully prepared via “one-pot” approach; tetramethoxysilane and 3-mercaptopropyltrimethoxysilane were mixed together with the porogens in ice bath before being injected into the fused
Dr. Firda Furqani, Ilona Bella, Prima Fitria Hillman, Lee Wah Lim   +3 more
doaj   +1 more source