Selective CO formation in bicarbonate electrolysis is achieved by retaining reactive CO2 and tuning pH, while the competing hydrogen evolution reaction occurs at the interface. The rate‐determining step couples the chemical equilibrium of bicarbonate/CO2 with electrochemical charge transfer, offering insight into optimizing reaction conditions for ...
Lin Li +7 more
wiley +1 more source
Vanadium Pentoxide-Mediated Oxidation Coupled with HPLC-MS/MS for Broad-Spectrum Screening of Paralytic Shellfish Toxins in Plasma. [PDF]
Ma Y +5 more
europepmc +1 more source
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn +20 more
wiley +1 more source
Convenient Determination of Trace Methylcyclosiloxanes in Water by Vortex-Assisted Small-Scale Liquid-Liquid Extraction and GC-MS Analysis. [PDF]
Fang J +5 more
europepmc +1 more source
Mixed-mode capillary electrochromatographic separation of anionic analytes
In this work, mixed-mode capillary electrochromatography is introduced as a method for selectivity manipulation in the separation of charged analytes and is investigated for a number of analytes.
Emily Hilder (14739100) +2 more
core
Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
wiley +1 more source
Purification of Advanced Therapeutics by Flow-Through Pseudo-Affinity Chromatography: Bi-Specific mABs, Fc Fusion Proteins, and Adeno-Associated Viruses. [PDF]
Chu W +23 more
europepmc +1 more source
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu +10 more
wiley +1 more source
Antibiofilm activity against common pathogenic bacteria in Thailand and liquid chromatography-quadrupole time-of-flight mass spectrometry chemical profiling of Ha-Rak formula and its components: an in vitro study. [PDF]
Fondee S +3 more
europepmc +1 more source
The method presented uses a mixed-mode anion exchange SPE and liquid chromatography tandem mass spectrometry to analyze 5 sulfonylurea, 8 phenoxy acid, 12 triazine and 6 other herbicides in environmental waters.
P Zhang (7533767) +3 more
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