Results 121 to 130 of about 4,503,666 (319)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Modelling behavioural interactions of drivers' in mixed traffic conditions

Journal of Traffic and Transportation Engineering (English ed. Online), 2018
Mixed traffic conditions are often prevalent in developing economies such as India, China, Bangladesh, etc. and are characterised by the presence of multiple vehicle types.
Caleb Ronald Munigety
doaj   +1 more source

Optimal error estimates of a mixed finite element method for\ud parabolic integro-differential equations with non smooth initial data [PDF]

, 2010
In this article, a new mixed method is proposed and analyzed for parabolic integro-differential equations (PIDE) with nonsmooth initial data. Compared to mixed methods for PIDE, the present method does not bank on a reformulation using a resolvent ...
Goswami, D., Pani, A. K., Yadav, S
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Concurrent generation of multivariate mixed data with variables of dissimilar types [PDF]

, 2016
Anup Amatya, Hakan Demirtaş
openalex   +1 more source

Robust MM-Estimation and Inference in Mixed Linear Models [PDF]

Mixed linear models are used to analyse data in many settings. These models generally rely on the normality assumption and are often fitted by means of the maximum likelihood estimator (MLE) or the restricted maximum likelihood estimator (REML). However,
Samuel Copt, Stephane Heritier
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Organic farm incomes in England and Wales 2001/02 [PDF]

, 2004
Financial results from research work carried out for the Department of Environment, Food and Rural Affairs (DEFRA) by the Organic Farming Research Unit at the IRS, UWA on the economic performance of organic farms in 2001/02 are presented in this report ...
Fowler, Sue, Jackson, Andrew, Lampkin, Nicolas   +2 more
core  

VAEM: a Deep Generative Model for Heterogeneous Mixed Type Data

, 2020
Deep generative models often perform poorly in real-world applications due to the heterogeneity of natural data sets. Heterogeneity arises from data containing different types of features (categorical, ordinal, continuous, etc.) and features of the same type having different marginal distributions.
Ma, Chao, Tschiatschek, Sebastian, Hernandez-Lobato, Jose Miguel, Turner, Richard, Zhang, Cheng   +4 more
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source