Results 81 to 90 of about 4,503,666 (319)

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Sparse spectral-tau method for the three-dimensional helically reduced wave equation on two-center domains [PDF]

, 2011
We describe a multidomain spectral-tau method for solving the three-dimensional helically reduced wave equation on the type of two-center domain that arises when modeling compact binary objects in astrophysical applications.
Abramowitz, Adams, Andrade, Baker, Baker, Baker, Beetle, Beetle, Bičák, Boyle, Bromley, Brügmann, Campanelli, Campanelli, Campanelli, Campanelli, Campanelli, Centrella, Coutsias, Coutsias, Golub, González, Hernández, Hesthaven, Hill, Lau, Lousto, Lovelace, Mathews, Pfeiffer, Pretorius, Rezzolla, Richard H. Price, Scheel, Schott, Smith, Stephen R. Lau, Szilágyi, Thompson, Torres, von Winckel   +40 more
core   +3 more sources

Hierarchical clustering of mixed-type data based on barycentric coding

Behaviormetrika, 2022
Clustering of mixed-type datasets can be a particularly challenging task as it requires taking into account the associations between variables with different level of measurement, i.e., nominal, ordinal and/or interval. In some cases, hierarchical clustering is considered a suitable approach, as it makes few assumptions about the data and its solution ...
Moschidis, Odysseas, Markos, Angelos, Chadjipadelis, Theodore   +2 more
openaire   +2 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Comparison of genome-wide association methods in analyses of admixed populations with complex familial relationships. [PDF]

PLoS ONE, 2014
Population structure is known to cause false-positive detection in association studies. We compared the power, precision, and type-I error rates of various association models in analyses of a simulated dataset with structure at the population (admixture ...
Naveen K Kadri, Bernt Guldbrandtsen, Peter Sørensen, Goutam Sahana   +3 more
doaj   +1 more source

On the interpretation of the equilibrium magnetization in the mixed state of high-Tc superconductors

, 2004
We apply a recently developed scaling procedure to the analysis of equilibrium magnetization M(H) data that were obtained for T-2212 and Bi-2212single crystals and were reported in the literature.
Abrikosov, Brandt, Brandt, Bulaevskii, Cheon, Cho, Däumling, Gor'kov, H.R Ott, Hao, Hao, Helfand, I.L Landau, Kim, Kim, Kim, Kogan, Kogan, Landau, Landau, Landau, Landau, Landau, Landau, Li, Li, Li, Li, Pogosov, Thompson, Thompson, Zheng, Zhuo, Zhuo   +33 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

MissForest—non-parametric missing value imputation for mixed-type data [PDF]

, 2017
Motivation: Modern data acquisition based on high-throughput technology is often facing the problem of missing data. Algorithms commonly used in the analysis of such large-scale data often depend on a complete set.
Bühlmann, Peter, Stekhoven, Daniel J.
core  

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source