Results 81 to 90 of about 4,674,587 (322)

Online Asynchronous Learning over Streaming Nominal Data

open access: yesBig Data and Cognitive Computing
Online learning has become increasingly prevalent in real-world applications, where data streams often comprise heterogeneous feature types—both nominal and numerical—and labels may not arrive synchronously with features.
Hongrui Li   +7 more
doaj   +1 more source

A modification of the mixed form of Richards equation and its application in vertically inhomogeneous soils [PDF]

open access: yes, 2011
Recently, new soil data maps were developed, which include vertical soil properties like soil type. Implementing those into a multilayer Soil-Vegetation-Atmosphere-Transfer (SVAT) scheme, discontinuities in the water content occur at the interface ...
Ahrens, Bodo, Kalinka, Frank
core   +2 more sources

Towards Generating Adversarial Examples on Mixed-type Data

open access: yes, 2022
The existence of adversarial attacks (or adversarial examples) brings huge concern about the machine learning (ML) model's safety issues. For many safety-critical ML tasks, such as financial forecasting, fraudulent detection, and anomaly detection, the data samples are usually mixed-type, which contain plenty of numerical and categorical features at ...
Xu, Han   +6 more
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Comparison of genome-wide association methods in analyses of admixed populations with complex familial relationships. [PDF]

open access: yesPLoS ONE, 2014
Population structure is known to cause false-positive detection in association studies. We compared the power, precision, and type-I error rates of various association models in analyses of a simulated dataset with structure at the population (admixture ...
Naveen K Kadri   +3 more
doaj   +1 more source

MissForest—non-parametric missing value imputation for mixed-type data [PDF]

open access: yes, 2017
Motivation: Modern data acquisition based on high-throughput technology is often facing the problem of missing data. Algorithms commonly used in the analysis of such large-scale data often depend on a complete set.
Bühlmann, Peter, Stekhoven, Daniel J.
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

On the interpretation of the equilibrium magnetization in the mixed state of high-Tc superconductors

open access: yes, 2004
We apply a recently developed scaling procedure to the analysis of equilibrium magnetization M(H) data that were obtained for T-2212 and Bi-2212single crystals and were reported in the literature.
Abrikosov   +33 more
core   +1 more source

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