Results 71 to 80 of about 8,840,706 (291)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Research on the Transition Section Length of the Mixed Workface Using Gangue Backfilling Method and Caving Method

open access: yesOpen Geosciences, 2019
Aiming at the problem of the sudden increase of the working resistance of the support in the transition section of the mixed workface, this paper adopts the physical simulation to study the fracture and movement characteristics of the overburden strata ...
Tai Yang, Guo Shuai, Fang Kun
doaj   +1 more source

01-02 "Mixed Signals: Market Incentives, Recycling, and the Price Spike of 1995" [PDF]

open access: yes
Environmental economics assumes that reliance on price signals, adjusted for externalities, normally leads to efficient solutions to environmental problems. We explore a limiting case, when market volatility created "mixed signals": waste paper and other
Frank Ackerman, Kevin Gallagher
core  

Quantum Brachistochrone for Mixed States

open access: yes, 2006
We present a general formalism based on the variational principle for finding the time-optimal quantum evolution of mixed states governed by a master equation, when the Hamiltonian and the Lindblad operators are subject to certain constraints.
Carlini A   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Bus Travel TIME in the Mixed Traffic Based on Statistica Neural Network [PDF]

open access: yes, 2010
This paper presents the assessment of a number of factors affecting bus travel time and a relationship model between those factors and bus travel time. Statistica Neural Network (SNN) tool is used to solve this complex phenomenon.
Kamaruddin, I. (Ibrahim)   +3 more
core  

Flavor states of mixed neutrinos

open access: yes, 2007
By resorting to previous results on flavor mixing in Quantum Field Theory, we show how to consistently define flavor states of mixed neutrinos as eigenstates of the flavor charge operators.Comment: 4 pages, presented at 13th International Symposium on ...
A. Capolupo   +7 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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