Results 131 to 140 of about 923,003 (329)

Generalized solutions for singular double-phase elliptic equations under mixed boundary conditions

Nonlinear Analysis
In this article, we investigate at least one or two generalized solutions for double-phase singular elliptic equations with Hardy potential. We show the existence of at least one or two distinct generalized solutions under mixed boundary conditions via ...
Jian Liu, Zengqin Zhao
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Mixed Boundary Value Problems of a Transversely Isotropic Layer Under Torsion and Various Boundary Conditions

Engineering Transactions, 1983
This paper deals with the axially symmetric torsion of a transversely isotropic layer elastically supported at the lower plane or bonded with dissimilar half-space.
B. Rogowski
doaj  

Steady-state Navier–Stokes flow in an obstructed pipe under mixed boundary conditions and with a prescribed transversal flux rate [PDF]

, 2023
Gianmarco Sperone
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Modified Fourier-Galerkin Solution for Aerospace Skin-Stiffener Panels Subjected to Interface Force and Mixed Boundary Conditions. [PDF]

Materials (Basel), 2019
Hou R, Wang Q, Li J, Ke Y.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Fully automated tri-variational rebuilding of ideal solid-state models within mixed boundary conditions. [PDF]

Heliyon, 2019
Zongur A.
europepmc   +1 more source

Finite element convergence for the time-dependent Joule heating problem\n with mixed boundary conditions [PDF]

, 2018
Max Jensen, Axel Målqvist, Anna Persson
openalex   +1 more source