Results 111 to 120 of about 923,003 (329)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Stress-intensity factor calculations using the boundary force method [PDF]
The Boundary Force Method (BFM) was formulated for the three fundamental problems of elasticity: the stress boundary value problem, the displacement boundary value problem, and the mixed boundary value problem.
Newman, J. C., Jr. +2 more
core +1 more source
Adaptive Boundary Element for the Problem with Mixed Boundary Condition.
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1995 This paper concerns a construction of adaptive boundary elements for the two-dimensional problems with mixed boundary conditions such as heat transfer condition between heated body surface and surrounding medium. The scheme is an extension of the method proposed by the present authors, called sample point error analysis and related error indicator for ...
Norio Kamiya, Yuji Aikawa, Ken Kawaguchi
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Mixed convective heat transfer to Sisko fluid over a radially stretching sheet in the presence of convective boundary conditions [PDF]
, 2015 Masood Khan, Rabia Malik, Asif Munir
openalex +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Boundary stabilization and control of wave equations by means of a general multiplier method
, 2009 We describe a general multiplier method to obtain boundary stabilization of the wave equation by means of a (linear or quasi-linear) Neumann feedback. This also enables us to get Dirichlet boundary control of the wave equation.
Cornilleau, Pierre, Loheac, Jean-Pierre
core +1 more source
Multiple Solutions of Second-Order Damped Impulsive Differential Equations with Mixed Boundary Conditions [PDF]
, 2014 Jian Liu, Lizhao Yan
openalex +1 more source