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Unraveling Complexity: A Case of Possible Overlapping Between Mixed Connective Tissue Disease and Systemic Lupus Erythematosus With Renal Involvement. [PDF]

Cureus
Smith D, Reid DM, Mascio AA, Noel BO, Giangreco M.   +4 more
europepmc   +1 more source

Mixed Connective Tissue Disease

Current Opinion in Rheumatology, 2000
A defining feature of mixed connective tissue disease (MCTD) is the presence of antibodies against the U1-ribonucleoprotein (RNP) complex, but other autoantibodies in MCTD have recently been described. Research has also further elucidated the immune responses directed against U1-RNP in humans and in murine models of disease.
R W, Hoffman, E L, Greidinger
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Mixed connective tissue disease

Lupus, 2006
Mixed connective tissue disease (MCTD) was first described in 1972 as a disease syndrome with overlapping features of systemic sclerosis, systemic lupus erythematosus (SLE) and polymyositis associated with antibodies to RNAse sensitive extractable nuclear antigen.
P J W Venables
exaly   +3 more sources

Mixed connective tissue disease

Best Practice and Research in Clinical Rheumatology, 2016
The concept of mixed connective tissue disease (MCTD) as a separate connective tissue disease (CTD) has persisted for more than four decades. High titers of antibodies targeting the U1 small nuclear ribonucleoprotein particle (U1 snRNP) in peripheral blood are a sine qua non for the diagnosis of MCTD, in addition to distinct clinical features including
Siri Opsahl Hetlevik, Ragnar Gunnarsson, Øyvind Molberg   +2 more
exaly   +3 more sources

Esophageal involvement and interstitial lung disease in mixed connective tissue disease [PDF]

Respiratory Medicine, 2009
SummaryRationaleMixed connective tissue disease is a systemic inflammatory disorder that results in both pulmonary and esophageal manifestations.ObjectivesWe sought to evaluate the relationship between esophageal dysfunction and interstitial lung disease
Tomas Navarro-Rodriguez, C R R Carvalho
exaly   +2 more sources

Mixed connective tissue disease

Clinics in Dermatology, 1985
Abstract Mixed connective tissue disease (MCTD) was first described by Gordon Sharp, 1 in 1972, as a distinct connective tissue disorder characterized by overlapping features of systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS), and dermato/polymyositis (DP/PM).
D T, Schreiner, J L, Jorizzo
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Mixed Connective-Tissue Disease

New England Journal of Medicine, 1977
Coping with chronic illness has become a personal experience for me. For the past 13 years, I have gone through various stages of coping with mixed connective tissue disease (MCTD), a rare collagen-vascular disease of unknown origin that resembles scleroderma, lupus erythematosus, and polymyositis.
openaire   +4 more sources