Results 61 to 70 of about 204,635 (325)

Capillaroscopy in 2016 : new perspectives in systemic sclerosis [PDF]

open access: yes, 2016
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by early impairment of the microvascular system. Nailfold microangiopathy and decreased peripheral blood perfusion are typical clinical aspects of SSc.
Cutolo, M   +6 more
core   +1 more source

The pathogenesis of tendinopathy. A molecular perspective [PDF]

open access: yes, 2004
There are many publications that discuss the aetiology, diagnosis and treatment of the various forms of tendinopathy, but few are based on conclusive scientific evidence.
Riley, GP
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Bronchiolitis obliterans. [PDF]

open access: yes, 1989
Bronchiolitis obliterans in the adult patient is a relatively uncommon and vexing clinical entity. This confusion results because this pathologic finding occurs in a variety of diverse clinical settings.
King, TE
core  

Broadband hyperspectral imaging for breast tumor detection using spectral and spatial information [PDF]

open access: yes, 2019
Complete tumor removal during breast-conserving surgery remains challenging due to the lack of optimal intraoperative margin assessment techniques. Here, we use hyperspectral imaging for tumor detection in fresh breast tissue.
Dashtbozorg, Behdad   +5 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An uncommon manifestation of mixed connective tissue disorder presenting as dilated cardiomyopathy

open access: yesHeart India
Mixed connective tissue disorder is a systemic autoimmune disorder that can affect any organ in the system including the heart. Varied cardiac manifestation of mixed connective tissue disease has been reported including pericarditis, pulmonary ...
Ashok Jain
doaj   +1 more source

Mixed Connective Tissue Disease with Severe Axonal Polyneuropathy: A Case Report

open access: yesOman Medical Journal, 2022
Mixed connective tissue disease (MCTD) is a unique disorder characterized by the presence of a high titer of anti-U1 ribonucloprotein antibody with overlapping features of various connective tissue disorders including systemic lupus erythematosus ...
Talal Al Lawati, Batool Hassan
doaj   +1 more source

Prevalence of pulmonary hypertension in patients with systemic sclerosis and mixed connective tissue disease

open access: yesMedicine, 2018
Systemic sclerosis (SSc) and mixed connective tissue disease (MCTD) are 2 conditions in which pulmonary hypertension (PH) can develop. We retrospectively analyzed the probability of PH in case of 83 patients (69 SSc and 14 MCTD).
K. Niklas   +3 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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