Results 41 to 50 of about 215 (89)

Uncharted territory: retinal vasculitis and cryoglobulinemia in Behçet’s disease – a case report

Frontiers in Immunology
Behçet’s disease (BD) is a systemic inflammatory disorder characterized by recurrent oral and genital ulcers, skin lesions, and ocular involvement, often presenting with retinal vasculitis as a severe complication.
Yadan Zou, Kun Yang, Xiaoying Zhang, Sheng-Guang Li   +3 more
doaj   +1 more source

Type III Mixed Cryoglobulinemia and Antiphospholipid Syndrome in a Patient With Partial DiGeorge Syndrome

Clinical and Developmental Immunology, 2006
We studied a 14 year-old boy with partial DiGeorge syndrome (DGS), status post complete repair of Tetralogy of Fallot, who developed antiphospholipid syndrome (APS) and type III mixed cryoglobulinemia.
Alice D. Chang, Raffi Tachdjian, Kerry Gallagher, Deborah K. McCurdy, Charles Lassman, E. Richard Stiehm, Ora Yadin   +6 more
doaj   +1 more source

Laboratory Practices for the Detection and Characterization of Cryoglobulins and Cryofibrinogen

Journal of Clinical Laboratory Analysis, Volume 39, Issue 15, August 2025.
This study shows the importance of carrying out the search for both cryoproteins, cryoglobulins, and cryofibrinogen in cases of strong clinical suspicion of cryoproteinemia, despite their complex but not impossible detection. Use of correct procedures from the pre‐preanalytical phase up to reporting, of alternative methods such as immunotyping and the ...
Teresa Troiano, Anna Marinaccio, Pamela Patierno, Alessandra Di Geronimo, Lucia Demarinis, Francesca Di Serio   +5 more
wiley   +1 more source

Mixed cryoglobulinemia as a potential indicator of clinically silent Hepatitis C infection

Translation
Hepatitis C virus (HCV) is one of the major causes of chronic liver disease and its prevalence is increasing worldwide. There are many extra hepatic manifestations of Hepatitis C infection including B –cell lymphoproliferative disorders.
Asif Islam, Salar Haider, Shehroze Tabassum, Aroma Naeem   +3 more
doaj   +1 more source

Clearance of Hepatitis C Viremia During Direct‐Acting Antiviral Therapy Leads to Rapid Changes in Lipid and Lipoprotein Metabolism

Alimentary Pharmacology &Therapeutics, Volume 62, Issue 2, Page 146-158, July 2025.
HCV clearance during direct‐acting antiviral therapy rapidly increases serum lipids and lipoproteins, potentially elevating cardiovascular risk. These metabolic changes, mediated by genes regulating hepatic lipogenesis, suggest that lipid levels should be closely monitored post‐SVR to assess long‐term cardiovascular implications.
Zahra Sarrafan‐Chaharsoughi, Varun Takyar, Sungyoung Auh, Gavin Nee, Ahmad Alawad, Brent S. Abel, Devika Kapuria, Colleen Byrnes, Anna Wolska, David E. Kleiner, Robert Shamburek, Alan T. Remaley, Marc G. Ghany   +12 more
wiley   +1 more source

Extrahepatic Replication and Genomic Signatures of the Hepatitis E Virus in the Kidney

Liver International, Volume 45, Issue 7, July 2025.
ABSTRACT Introduction The hepatitis E virus (HEV; species Paslahepevirus balayani) is a common human pathogenic and zoonotic virus that can cause both acute fulminant and chronic hepatitis. Despite its reputation as a hepatotropic virus, HEV infection is also associated with a number of extrahepatic diseases, including kidney disorders.
Avista Wahid, Nele Meyer, Christine Wundes, Lucas Hüffner, Saskia Janshoff, Nicola Frericks, Martina Friesland, Katja Dinkelborg, Elmira Aliabadi, Fenja Laue, Markus Cornberg, Benjamin Maasoumy, Birgit Bremer, Sven Pischke, Tobias Müller, Julian Zur Schulze Wiesch, Julia Benckert, Rainer G. Ulrich, Svenja Hardtke, Petra Dörge, Florian Vondran, Ansgar Lohse, Michael Peter Manns, Daniel Todt, Heiner Wedemeyer, Thomas Pietschmann, Eike Steinmann, André Gömer, Patrick Behrendt   +28 more
wiley   +1 more source

Non-infectious mixed cryoglobulinemia as a new clinical presentation of mutation in the gene encoding coatomer subunit alpha: a case report of two adult sisters

Frontiers in Immunology
Cryoglobulinemia is a rare disease characterized by the presence of cryoglobulins in the blood serum. It is usually caused by autoimmune, lymphoproliferative, or infectious factors.
Ksymena Leśniak, Rafał Płoski, Małgorzata Rydzanicz, Aleksandra Rymarz, Arkadiusz Lubas, Tomasz Syryło, Stanisław Niemczyk   +6 more
doaj   +1 more source

Hospitalisations With Cryoglobulin‐Related Diseases in Spain Over 25 Years

Liver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background The epidemiology of cryoglobulinemia in Spain has likely changed following the widespread adoption of direct‐acting antivirals (DAAs) since 2015 for the treatment of hepatitis C virus (HCV) infection, the principal cause of mixed cryoglobulinemia (MC).
Mario Martín‐Portugués, Jorge Esteban‐Sampedro, Carmen de Mendoza, Guillermo Ruiz‐Irastorza, Ana Royuela, Alfonso Ortega‐de la Puente, Marina de la Cruz‐Echeandía, Xiomara Patricia Blanco‐Valencia, Vicente Soriano, Víctor Moreno‐Torres   +9 more
wiley   +1 more source

Case Report: A case of type II cryoglobulinemia secondary to diffuse large B-cell lymphoma

Frontiers in Oncology
BackgroundDiffuse Large B-Cell Lymphoma (DLBCL) represents the most prevalent subtype of Non-Hodgkin Lymphoma (NHL). Cryoglobulinemia results from reversible precipitation of serum immunoglobulin complexes at low temperatures, with Type II (mixed ...
Cuiping Mao, Xiaohe Hao
doaj   +1 more source

Case Report: Borderline type I/II cryoglobulinemia associated with marginal zone lymphoma: a diagnostic challenge

Frontiers in Oncology
Cryoglobulinemia comprises heterogeneous disorders caused by immunoglobulins that precipitate at low temperatures, leading to vascular occlusion and immune–mediated tissue injury.
Fabiana Crispo, Giovanna Mansueto, Francesca Pia Scioscia, Massimo Dante Di Somma, Diego Petrilli, Biagina Campisi, Fiorella D’Auria, Giulia Anna Carmen Vita, Giovanni D’Arena, Gabriella Bianchino   +9 more
doaj   +1 more source