Results 81 to 90 of about 3,064,383 (240)
, 2007 Longitudinal data tracking repeated measurements on individuals are highly valued for research because they offer controls for unmeasured individual heterogeneity that might otherwise bias results.
Lockwood, J. R., McCaffrey, Daniel F.
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Mixed Effects Analysis of Height Growth in Ethiopian Children Aged 1-12 Years: A Cohort Study
East African Journal of Biophysical and Computational SciencesModelling physical growth is a key component to examine and identify definingcharacteristics in the growth process.The goal of this study was to model and captureknown features of height growth in Ethiopian children aged 1–12 years.
Dereje Danbe Debeko, Ayele Taye Goshu
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Handling Missing Values in Interrupted Time Series Analysis of Longitudinal Individual-Level Data
Clinical Epidemiology, 2020 Juan Carlos Bazo-Alvarez,1,2 Tim P Morris,3 Tra My Pham,3 James R Carpenter,3,4 Irene Petersen1,5 1Research Department of Primary Care and Population Health, University College London (UCL), London, UK; 2Instituto de Investigación, Universidad Cat&
Bazo-Alvarez JC +4 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
MODELOS Y ANÁLISIS PARA DATOS DE DEGRADACIÓN MODELOS Y ANÁLISIS PARA DATOS DE DEGRADACIÓN
Revista Colombiana de Estadística, 2003 Degradation is a weakness that eventually can cause failure (e.g. car tire wear). When it is possible to measure degradation, such measures often provide more information than failure-time data for purposes of assessing and improving product reliability.
Yánez C. Sergio +2 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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MathematicsRestricted maximum likelihood (REML) estimators are commonly used to obtain unbiased estimators for the variance components in linear mixed models. In modern applications, particularly in genomic studies, the dimension of the design matrix with respect ...
Xiaoxi Shen, Qing Lu
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