Results 101 to 110 of about 937,585 (316)
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
A Graph Theoretic Perspective on CPM(Rel) [PDF]
Electronic Proceedings in Theoretical Computer Science, 2015 Mixed states are of interest in quantum mechanics for modelling partial information. More recently categorical approaches to linguistics have also exploited the idea of mixed states to describe ambiguity and hyponym / hypernym relationships.
Daniel Marsden
doaj +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
, 2015 We have generalised the concept of graph states to what we have called mixed graph states, which we define in terms of mixed graphs, that is graphs with both directed and undirected edges, as the density matrix stabilized by the associated stabilizer matrix defined by the mixed graph.
Riera, Constanza +2 more
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Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
m-step inverse fuzzy mixed competition graphs
International Journal of Mathematics for IndustryThe notion of competition graphs has a wide range of applications and has been utilized in designing various ecological problems and real-world competitions.
Rahul Mondal, Ganesh Ghorai
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
On the mixed domination problem in graphs
Theoretical Computer Science, 2013 A mixed dominating set of a simple graph G=(V,E) is a subset [email protected][email protected]?E such that every vertex or edge not in D is adjacent or incident to at least one vertex or edge in D. The mixed domination problem is to determine a minimum mixed dominating set of G.
James K. Lan, Gerard J. Chang
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Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source