Results 41 to 50 of about 2,896,689 (257)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

An Approach for Mixed Upward Planarization

open access: yesJournal of Graph Algorithms and Applications, 2003
In this paper, we consider the problem of finding a mixed upward planarization of a mixed graph, i.e., a graph with directed and undirected edges. The problem is a generalization of the planarization problem for undirected graphs and is motivated by ...
Markus Eiglsperger   +2 more
doaj   +1 more source

The Vertex-Edge Resolvability of Some Wheel-Related Graphs

open access: yesJournal of Mathematics, 2021
A vertex w∈VH distinguishes (or resolves) two elements (edges or vertices) a,z∈VH∪EH if dw,a≠dw,z. A set Wm of vertices in a nontrivial connected graph H is said to be a mixed resolving set for H if every two different elements (edges and vertices) of H ...
Bao-Hua Xing   +4 more
doaj   +1 more source

Multi-Scale Mixed Dense Graph Convolution Network for Skeleton-Based Action Recognition

open access: yesIEEE Access, 2021
In skeleton-based action recognition, the approaches based on graph convolutional networks(GCN) have achieved remarkable performance by modeling spatial-temporal graphs to explore the physical dependencies between body joints.
Hailun Xia, Xinkai Gao
doaj   +1 more source

Forcing (G,D)-number of a Graph [PDF]

open access: yes, 2011
By a graph G=(V,E), we mean a finite, undirected connected graph without loops and multiple ...
Nagarajan, A.   +3 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Some results concerning the solution mappings of mixed variational inequality problems

open access: yesJournal of Inequalities and Applications, 2016
This paper shows some continuities of mappings between the space of mixed variational inequality problems and the graph space of their solution mappings.
Qi-Qing Song, Hui Yang
doaj   +1 more source

Maximization of the Spectral Gap for Chemical Graphs by means of a Solution to a Mixed Integer Semidefinite Program [PDF]

open access: yesComputer Methods in Materials Science, 2016
In this paper we analyze the spectral gap of a weighted graph which is the difference between the smallest positive and largest negative eigenvalue of its adjacency matrix. Such a graph can represent e.g. a chemical organic molecule.
Soňa Pavlíková, Daniel Ševčovič
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

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