Results 61 to 70 of about 2,896,689 (257)

Triple Connected Domination Number of a Graph [PDF]

open access: yes, 2012
The concept of triple connected graphs with real life application was introduced by considering the existence of a path containing any three vertices of a graph G.
Selvam Avadayappan   +7 more
core   +1 more source

A Self-Supervised Mixed-Curvature Graph Neural Network

open access: yes, 2022
Graph representation learning received increasing attentions in recent years. Most of the existing methods ignore the complexity of the graph structures and restrict graphs in a single constant-curvature representation space, which is only suitable to ...
Peng, Hao   +6 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

An efficient algorithm for computing interventional distributions in latent variable causal models

open access: yes, 2011
Probabilistic inference in graphical models is the task of computing marginal and conditional densities of interest from a factorized representation of a joint probability distribution.
Richardson, Thomas S.   +2 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Graph Algorithm Animation with Grrr [PDF]

open access: yes, 2000
We discuss geometric positioning, highlighting of visited nodes and user defined highlighting that form the algorithm animation facilities in the Grrr graph rewriting programming language. The main purpose of animation was initially for the debugging and
Peter J. Rodgers   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Mixed graph edge coloring [PDF]

open access: yes, 2019
We are interested in coloring the edges of a mixed graph, i.e., a graph containing unoriented and oriented edges. This problem is related to a communication problem in job-shop scheduling systems.
Żyliński, Paweł   +3 more
core  

Graph-based implicit knowledge discovery from architecture change logs [PDF]

open access: yes, 2012
Service architectures continuously evolve as a consequence of frequent business and technical change cycles. Architecture change log data represents a source of evolution-centric information in terms of intent, scope and operationalisation to ...
Pooyan Jamshidi (5276344)   +12 more
core   +2 more sources

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