Results 141 to 150 of about 1,978,652 (350)

A Mixed Reality Cognitive Orthosis to Support Older Adults in Achieving Their Daily Living Activities: Focus Group Study With Clinical Experts [PDF]

, 2022
Amel Yaddaden, Guillaume Spalla, Charles Gouin-Vallerand, Patricia Briskie-Semeniuk, Nathalie Bier   +4 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Irregular Wave Groups Simulation Based on Semi-Mixed Eulerian-Lagrangian Boundary Element Method

Shanghai Jiaotong Daxue xuebao
In order to effectively simulate irregular wave groups that better represent the characteristics of real waves, a numerical wave tank based on a semi-mixed Eulerian-Lagrangian algorithm combined with boundary element method was developed in conjunction ...
XUE Wen, GAO Zhiliang
doaj   +1 more source

Direct Sums of Self-Small Mixed Groups

, 1999
The class G of self-small mixed abelian groups of finite rank has recently been the focus of a number of investigations. It is known that, up to quasi-isomorphism, G is dual to the category of locally free torsion-free abelian groups of finite rank.
Wickless, W, Files, S
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Intersections of Gender, Ethnicity, and Socioeconomic Position in Health in England: A Mixed Methods Study [PDF]

, 2011
Background: Social inequalities in health represent one of the greatest challenges to public health today. Traditionally, studies investigating health inequalities have treated gender, ethnicity, and socioeconomic position as independent and additive ...
Hartnell, Sally J
core  

Overcoming barriers to equality, diversity, inclusivity, and sense of belonging in healthcare education: the Underrepresented Groups’ Experiences in Osteopathic Training (UrGEnT) mixed methods study. [PDF]

Background: Individuals from minority groups have historically faced social injustices. Those from underrepresented groups have been less likely to access both healthcare services and higher education.
Abbey, H., Thomson, O.P., MacMillan, A., Hammond, J.A., Vogel, S., Draper-Rodi, J., Brownhill, K., Fabusuyi, Y.   +7 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Using Social Network Analysis to Assess ‘Groupness’ in a Mixed-Species Zoo Exhibit of Tufted Capuchins (Sapajus apella) and Squirrel Monkeys (Saimiri sciureus)

Animals
Mixed-species groups have been recorded in various primates, including tufted capuchin and squirrel monkeys. Measures of their ‘groupness’ are typically based on factors such as group stability, social interactions, proximity, or behavioural coordination.
Sophia Daoudi-Simison, Phyllis Lee, Hannah M. Buchanan-Smith   +2 more
doaj   +1 more source