Results 241 to 250 of about 4,540,525 (328)

Impact of the Synthetic Strategy on the Structure and Availability of Active Sites in Bifunctional Mesoporous Organic-Inorganic Hybrids. [PDF]

Materials (Basel)
Fernandes Pape Brito JC, Ancora G, Miletto I, Gianotti E.   +3 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Understanding healthy eating and physical activity community-centred behaviour change interventions for underserved populations: A mixed methods rapid review. [PDF]

Br J Health Psychol
Marshall J, Minihane AM, Jong ST, Hanson S, Akter S, Garner N, Hardeman W.   +6 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Effects of Instruction-Guided Attentional Focus on Jump Performance in Women's Artistic Gymnastics. [PDF]

Eur J Sport Sci
Veit J, Brinkschulte M, Vogt T.
europepmc   +1 more source

Staff and Culture's Role in Contribution to Social Justice in Residential Cyc Group Homes A Mixed Method Research's Utility in Organizational Development – Focusing on the Used Tense's Meaning in Verbal Manifestations

Zsolt Balázs Major, Anna Demjén, Enikő Kovács, Tünde Proksa, Kata Barabás, Orsolya Szőke   +5 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Generalizing an outbreak cluster detection method for two groups: an application to rabies. [PDF]

R Soc Open Sci
Hayes S, Lushasi K, Changalucha J, Sikana L, Hampson K, Donnelly CA, Nouvellet P.   +6 more
europepmc   +1 more source

Exploring Patients’ Perceptions and Experiences of a Telehealth-Based Group Breathing Intervention For Chronic Pain: A Mixed Methods Pilot Study

Asta Fung, Kerith Duncanson, Manasi Murthy Mittinty, Anne E. Vertigan, Suzanne J. Snodgrass   +4 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source