Results 121 to 130 of about 133,001 (290)

Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan   +10 more
wiley   +1 more source

Development of nutritionally balanced and acceptable army ration packs : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Product Development at Massey University [PDF]

open access: yes, 1987
Pg 198 not in original - misnumberedNutritionally balanced and consumer acceptable one man ration packs were developed for the N.Z. Army. The rations were designed quantitatively, using firstly mixed integer linear programming and secondly, menu planning
Soo, Bing David
core  

Multiobjective Optimization of Mixed-Integer Linear Programming Problems: A Multiparametric Optimization Approach. [PDF]

open access: yesInd Eng Chem Res, 2021
Pappas I   +6 more
europepmc   +1 more source

Optimizing Mine Ventilation Systems: An Advanced Mixed-Integer Linear Programming Model

open access: yesMathematics
In the underground mine ventilation area, the absence of robust solutions for nonlinear programming models has impeded progress for decades. To overcome the enduring difficulty of solving nonlinear optimization models for mine ventilation optimization, a
Deyun Zhong   +4 more
doaj   +1 more source

Integer Processing for Mixed Integer Linear Programming Problems

open access: yesInternational Journal of Mathematics And Computer Research
The mixed integer nonlinear programming problem addressed in this paper refers to mathematical pro­gramming with continuous and discrete variables and linearities in the ob­jective function and constraints. The purpose of this article is to create an approach to solving MILP problems for integer search through active constraints, and neighborhoods, in ...
Hardi Tambunan, Herman Mawengkang
openaire   +2 more sources

Short‐Term Scheduling Optimization of a Single‐Pipeline Refining System With High Melting Point Crude Oil

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT In order to reflect the actual production situation more comprehensively and optimize the production cost, this paper solves the short‐term scheduling optimization problem for a single pipeline containing high melting point crude oil. Based on the refining plan given by the upper layer, a multi‐objective optimization model with high melting ...
Jing Yao   +5 more
wiley   +1 more source

k‐Selective Electrical‐to‐Magnon Transduction with Finite‐Element‐Resolved Sub‐Micron Nanoantennas

open access: yesAdvanced Physics Research, EarlyView.
We introduce a coupled finite‐element‐finite‐difference framework that links impedance‐matched nanoantenna geometries to propagating spin‐wave dynamics, capturing skin effects, proximity effects, and taper leakage beyond uniform‐current models. Applied to coplanar‐waveguide and stripline nanoantennas on yttrium‐iron‐garnet, the simulations achieve ...
Andreas Höfinger   +11 more
wiley   +1 more source

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