Results 81 to 90 of about 4,094,616 (298)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Double-layer structure in the boundary layer over the Baltic Sea

open access: yes, 2005
Double-layered structures found over the Baltic Sea are investigated using radiosoundings and lidar measurements. Situations with double-layer structures are also simulated with the regional model REMO in a realistic manner.
Smedman, A. S.   +10 more
core   +1 more source

Study on Acoustic Variability Affected by Upper Ocean Dynamics in South Eastern Arabian Sea

open access: yesEarth and Space Science
The influence of upper ocean dynamics on the acoustic field in the South Eastern Arabian Sea (SEAS) is studied using in situ oceanographic/acoustic measurements from a moored buoy, along with satellite‐derived and climatological data sets.
Kotta Srinivasu   +6 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Ordered mixed-layer structures in the Mighei carbonaceous chondrite matrix

open access: yes, 1982
High resolution transmission electron microscopy of the Mighei carbonaceous chondrite matrix has revealed the presence of a new mixed layer structure material.
Mackinnon, Ian D.R.
core  

Characteristics of Mixed Layer Depth and Its Effect on Concentration of Chlorophyll-a (Karakteristik Mixed Layer Depth dan Pengaruhnya Terhadap Konsentrasi Klorofil-a)

open access: yesIlmu Kelautan, 2015
Perairan Selat Badung memiliki karakteristik yang sebagian besar dipengaruhi oleh aktivitas Arus Lintas Indonesia (ARLINDO). Pencampuran massa air akibat pergerakan massa air vertikal menjadikan kondisi lapisan yang homogen, dimana nilai suhu, salinitas ...
Novita Ayu Ryandhini   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

An examination of historical mixed layer depths along Line P in the Gulf of Alaska

open access: yes, 2005
Mixed layer depth (MLD) is computed, based upon historical measurements along Line P, in the Gulf of Alaska. Forty-six years of data are used for the monthly climatological calculations.
Myers, Paul G.   +2 more
core   +1 more source

Separation of neutral lipids of shark liver by “dry-column” chromatography

open access: yesJournal of Lipid Research, 1969
“Dry-column” chromatography in mixed solvents has been successfully used to separate gram quantities of neutral lipids from shark liver oil into simpler fractions.
Adria C. Casey
doaj   +1 more source

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