Results 11 to 20 of about 4,106,343 (229)

LinDA: linear models for differential abundance analysis of microbiome compositional data [PDF]

open access: yesGenome Biology, 2021
Differential abundance analysis is at the core of statistical analysis of microbiome data. The compositional nature of microbiome sequencing data makes false positive control challenging. Here, we show that the compositional effects can be addressed by a
Huijuan Zhou   +3 more
semanticscholar   +1 more source

BLMM: Parallelised computing for big linear mixed models

open access: yesNeuroImage, 2022
Within neuroimaging large-scale, shared datasets are becoming increasingly commonplace, challenging existing tools both in terms of overall scale and complexity of the study designs.
Thomas Maullin-Sapey, Thomas E. Nichols
doaj   +1 more source

Variational Bayesian Inference in High-Dimensional Linear Mixed Models

open access: yesMathematics, 2022
In high-dimensional regression models, the Bayesian lasso with the Gaussian spike and slab priors is widely adopted to select variables and estimate unknown parameters. However, it involves large matrix computations in a standard Gibbs sampler.
Jieyi Yi, Niansheng Tang
doaj   +1 more source

Gradient boosting for linear mixed models [PDF]

open access: yesThe International Journal of Biostatistics, 2021
Abstract Gradient boosting from the field of statistical learning is widely known as a powerful framework for estimation and selection of predictor effects in various regression models by adapting concepts from classification theory. Current boosting approaches also offer methods accounting for random effects and thus enable prediction ...
Griesbach, Colin   +2 more
openaire   +5 more sources

Extension of the glmm.hp package to Zero-Inflated Generalized Linear Mixed Models and multiple regression

open access: yesJournal of Plant Ecology, 2023
glmm.hp is an R package designed to evaluate the relative importance of collinear predictors within generalized linear mixed models (GLMMs). Since its initial release in January 2022, it has rapidly gained recognition and popularity among ecologists ...
Jiangshan Lai   +3 more
semanticscholar   +1 more source

Polygenic modeling with bayesian sparse linear mixed models. [PDF]

open access: yesPLoS Genetics, 2013
Both linear mixed models (LMMs) and sparse regression models are widely used in genetics applications, including, recently, polygenic modeling in genome-wide association studies.
Xiang Zhou   +2 more
doaj   +1 more source

CytoGLMM: conditional differential analysis for flow and mass cytometry experiments

open access: yesBMC Bioinformatics, 2021
Background Flow and mass cytometry are important modern immunology tools for measuring expression levels of multiple proteins on single cells. The goal is to better understand the mechanisms of responses on a single cell basis by studying differential ...
Christof Seiler   +7 more
doaj   +1 more source

Multiple testing correction in linear mixed models. [PDF]

open access: yes, 2016
BackgroundMultiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes ...
Eskin, Eleazar   +3 more
core   +2 more sources

Report Quality of Generalized Linear Mixed Models in Psychology: A Systematic Review

open access: yesFrontiers in Psychology, 2021
Generalized linear mixed models (GLMMs) estimate fixed and random effects and are especially useful when the dependent variable is binary, ordinal, count or quantitative but not normally distributed.
Roser Bono, R. Alarcón, M. Blanca
semanticscholar   +1 more source

Bayesian Linear Mixed Models with Polygenic Effects

open access: yesJournal of Statistical Software, 2018
We considered Bayesian estimation of polygenic effects, in particular heritability in relation to a class of linear mixed models implemented in R (R Core Team 2018).
Jing Hua Zhao   +2 more
doaj   +1 more source

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