Results 111 to 120 of about 2,903,354 (302)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Practical considerations of leading and working on a mixed methods project [PDF]
, 2010 The aim of this toolkit is to highlight key issues that might arise out of leading or working on a mixed methods research project. It will be useful for both Principal Investigators or project leaders, and other team members alike, and will offer a ...
Burke, Hazel, May, Vanessa
core
Mixed Methods for Mixed Models
, 2014 This work bridges the frequentist and Bayesian approaches to mixed models by borrowing the best features from both camps: point estimation procedures are combined with priors to obtain accurate, fast inference while posterior simulation techniques are developed that approximate the likelihood with great precision for the purposes of assessing ...
openaire +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Appraising Mixed Methods Research [PDF]
, 2018 There is increasing interest in the use of mixed methods research approaches among health researchers. While mixed methods research has the potential to reveal rich data and deeper understandings of complex phenomena, it needs to be evaluated with the ...
Elizabeth J. Halcomb +1 more
core +1 more source
Nursing OpenAim To understand how Black or African American women living with HIV (WLH) experience different types of stigma in their daily lives. Design Secondary analysis of quantitative and qualitative data from a recent clinical trial in Baltimore, Maryland ...
Tanya Mikhael +4 more
doaj +1 more source
Voices, 2015 “Mixed methods” (or “multiple methods” or “multiple strategy”) research design is a fairly new concept in music therapy research. It is inspired by recent methodological developments in the social sciences, covering the interaction of quantitative and ...
Lars Ole Bonde
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A mixed methods study exploring the factors and behaviours that impact on glycaemic control following a structured education programme: the Irish DAFNE Study [PDF]
, 2016 Aim: To explain the factors affecting glycemic control (measured by HbA1c) following theDose Adjustment for Normal Eating (DAFNE) program. Background: DAFNE is a structurededucation program designed to assist persons with type 1 diabetes mellitus achieve
Casey, Dympna +5 more
core +1 more source