Results 31 to 40 of about 2,086,696 (297)

Optimized D-α-tocopherol polyethylene glycol succinate/phospholipid self-assembled mixed micelles: A promising lipid-based nanoplatform for augmenting the antifungal activity of fluconazole [PDF]

, 2022
Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Usama A. Fahmy, Osama A. A. Ahmed, Nabil A. Alhakamy, Mahmoud A. Elfaky, Alaa Sirwi, Salman A. Hawsawi, Ali H. Alzahrani, Abdulrahman Y. Yaseen, Mohannad Qassim, Sabna Kotta   +11 more
openalex   +1 more source

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

Advanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

Mimicking Block Copolymer Self‐Assembly with One‐Pot Synthesized Polyphosphoester Gradient Copolymers

Advanced Functional Materials, EarlyView.
Degradable Polyphosphoester (PPE) gradient copolymers (GCPs) are synthesized via one‐pot copolymerization. We show that GCPs self‐assemble into nanostructures like polymersomes, effectively mimicking the behavior of traditional BCPs. The gradient strength is key, with softer gradients favoring micelles.
Suna Azhdari, Timo Rheinberger, Ulrich Mansfeld, Yorick Post, Jürgen Linders, Olga Koshkina, André H. Gröschel, Frederik R. Wurm   +7 more
wiley   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion

Advanced Healthcare Materials, EarlyView.
We have developed a smart hair‐repair ingredient based on β‐carboxylic acid amide that undergoes negative‐to‐positive charge conversion under mildly acidic conditions. The initial negative charge facilitates deep penetration into the hair fiber, while the subsequent positive charge enables re‐bonding with sulfonate groups in damaged hair keratin.
Sunyoung Kang, Serena Serin Park, Sugyeong Jeong, Seoyeon Kyung, Minjae Kim, Seok Kyun Yun, Hyun‐Na Kim, Seunghyun Kang, Yan Lee   +8 more
wiley   +1 more source

Paclitaxel prodrug based mixed micelles for tumor-targeted chemotherapy

, 2018
An effective chemotherapy is usually subject to an insufficient loading of hydrophobic drugs as well as severe side effects. In order to address these dilemmas in one formulation, we herein construct paclitaxel prodrug based mixed micelles (MMs) for ...
D. Tang, Xin Zhao, Tie Yang, Cheng Wang
semanticscholar   +1 more source

Improved oral absorption and anti-lung cancer activity of paclitaxel-loaded mixed micelles

Drug Delivery, 2017
The aim of this study was to establish a paclitaxel (PTX)-loaded mixed micelle delivery system (PTX-TP-M) with vitamin E-TPGS (TPGS) and Plasdone®S-630 Copovidone (PVPS630) as carriers to improve the solubility, oral absorption, and anti-tumor activity ...
Jian Hou, E. Sun, Zhen-hai Zhang, Jing Wang, Lei Yang, Li Cui, Zhongcheng Ke, Xiaobin Tan, X. Jia, Huixia Lv   +9 more
semanticscholar   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source