Results 41 to 50 of about 4,734,824 (293)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Fatigue life prediction under mixed-mode loading using equivalent stress intensity factor models
MATEC Web of Conferences, 2018 Damage tolerance principles are widely used to assess the structural integrity and failure of engineering components. The advances in numerical simulation techniques facilitate the prediction of fatigue life of engineering component, which is essential ...
Sajith S., Murthy K.S.R. K., Robi P.S.
doaj +1 more source
[Multilingualism and Mixed-Mode Communication
, 2023 Like other disciplines, the field of sociolinguistics is not a homogenous one. It rather comes in three “loosely connected waves” (Eckert 2012) with each wave applying specific sets of methods. How can we use methodological triangulation and combine these methods, both quantitative and qualitative in nature, to integrate the three waves of ...
openaire +2 more sources
Mixed-Mode Pandemic Modeling [PDF]
2019 Winter Simulation Conference (WSC), 2019 This paper describes a mixed mode approach to simulating a global pandemic. It describes the architectural and design decisions as well as the data sources, development tools and processes in each of the three simulation domains - System Dynamics (SD), Discrete Event Simulation (DES) and Agent-Based Modeling (ABM). The encompassing model uses a network
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Development of a Finite Element Methodology for Modelling Mixed-Mode Delamination Growth [PDF]
, 2007 A critical failure mechanism for composite skin-stiffened structures in compression is separation of the skin and stiffener, which can be considered analogous to interlaminar cracking.
Degenhardt, Richard +4 more
core
Characterizing Fatigue Delamination Growth in Multidirectional CFRP Laminates
Engineering ProceedingsDespite the popularity of multidirectional laminates in many fatigue-prone design applications, there is still little understanding of how the adjacent plies’ fibre orientation affects interfacial crack (delamination) fatigue propagation.
Davide Biagini +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Simulation of dynamic delamination and mode I energy dissipation [PDF]
, 2009 Delamination initiation and propagation of aeronautic composites is an active field of research. In this paper we present a methodology for critical energy release rate correlation of numerical simulation and experimental data.
Salaün, Michel +3 more
core
Strong embedded discontinuities for simulating fracture in quasi-brittle materials [PDF]
, 2011 In this paper embedded strong discontinuities are used to model discrete cracking in materials like concrete. In the approach followed a discontinuous displacement field is considered and the deformation is localized at a surface of zero width.
core +5 more sources