Results 61 to 70 of about 46,059 (265)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Measurement equivalence in mixed mode surveys
Frontiers in Psychology, 2015 Surveys increasingly use mixed mode data collection (e.g., combining face-to-face and web) because this controls costs and helps to maintain good response rates.
Joop J. Hox +2 more
doaj +1 more source
Mixed Mode Crack Propagation in Iliac Bone
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2021 Bone is a complex material that can be regarded as an anisotropic elastic composite material. The problem of crack propagation in human bone is analyzed by using a generalization of the maximum tensile stress criterion (MTS).
Baesu E. +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2012 Copyright @ 2012 Springer VerlagThis paper is concerned with the state estimation problem for a new class of discrete-time neural networks with Markovian jumping parameters and mixed time-delays.
Liu, Y, Liu, X, Wang, Z
core +1 more source
Reconfigurable Mixed Mode Universal Filter
Active and Passive Electronic Components, 2014 This paper presents a novel mixed mode universal filter configuration capable of working in voltage and transimpedance mode. The proposed single filter configuration can be reconfigured digitally to realize all the five second order filter functions ...
Neelofer Afzal, Devesh Singh
doaj +1 more source
THE ROLE OF MODE MIXING IN THE ABSORPTION OFp-MODES [PDF]
The Astrophysical Journal, 2009 Observations show that a p-mode may lose up to 70% of its energy flux when it interacts with a sunspot. Part of the absorbed energy is assumed to be converted into other types of waves, while part of it is re-emitted into modes with different radial orders n.
Gordovskyy, M., Jain, R., Hindman, B.W.
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source