Results 81 to 90 of about 46,059 (265)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
VDGA-Based Resistorless Mixed-Mode Universal Filter and Dual-Mode Quadrature Oscillator
Applied SciencesThis study introduces an electronically tunable resistorless mixed-mode universal filter and dual-mode quadrature oscillator configuration utilizing merely two voltage differencing gain amplifiers and two grounded capacitors.
Orapin Channumsin +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Development of a Finite Element Methodology for Modelling Mixed-Mode Delamination Growth
, 2007 A critical failure mechanism for composite skin-stiffened structures in compression is separation of the skin and stiffener, which can be considered analogous to interlaminar cracking.
Degenhardt, Richard +4 more
core
On the delamination suppression in structural joints by Z-fibre pinning [PDF]
, 2007 The main objective of this paper is to investigate the benefits of Z-fibre pinning to improve the bonding strength of composite joints. The problem is addressed from a design point of view in order to develop a simulation methodology that can be ...
Allegri, Giuliano +3 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
EPJ Web of Conferences, 2010 Usually the element of real structures is subject of the mixed mode loadings. This fact can be explained by the elements geometry and the loading orientations.
Absi J., Dubois F., Pop O., Meite M.
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Thermal sensitivity and adaptive comfort in mixed-mode office buildings in humid subtropical climate
, 2023 This study evaluates thermal sensitivity, expectations, and adaptability in mixed-mode ventilated buildings by subjective and objective assessments. A field study of simultaneous measurements of physical environmental parameters and right-here-right-now ...
Khoshbakht, Maryam +3 more
core +1 more source
Mixed-Mode: Past, Present, and Future
Survey Research Methods, 2018 Mixed-mode surveys have been around since the late 1980s. In the past thirty years, major changes in technology and society influenced and changed data collection and survey methodology. However, in those years, mixed-mode strategies remained part of the
Edith D. DeLeeuw
doaj +1 more source